Mikhail N, Ehsanipoor K
Department of Internal Medicine Education, Memorial Medical Center, Savannah, Ga, USA.
South Med J. 1999 Dec;92(12):1162-6. doi: 10.1097/00007611-199912000-00005.
Hypomagnesemia has been described in diabetes mellitus. We sought to compare serum total and ionized magnesium (Mg) levels in patients with type 2 diabetes with control subjects and to determine the relationship between diabetes control, as assessed by hemoglobin A1c (Hb A1c) and Mg (total and ionized).
Serum ionized Mg was measured by ion-selective electrode (ISE) method using the NOVA electrode.
Serum ionized Mg was significantly higher in diabetics than in control subjects, whereas no difference was found in total Mg. Serum ionized Mg correlated with total Mg in diabetics and in control subjects. There was an inverse correlation between total Mg and Hb A1c; the correlation was not statistically significant between ionized Mg and Hb A1c.
Our data do not support routine Mg supplementation or monitoring in type 2 diabetes.
糖尿病患者中已发现低镁血症。我们试图比较2型糖尿病患者与对照者的血清总镁和离子镁（Mg）水平，并确定通过糖化血红蛋白（Hb A1c）评估的糖尿病控制情况与镁（总镁和离子镁）之间的关系。
使用NOVA电极通过离子选择性电极（ISE）法测量血清离子镁。
糖尿病患者的血清离子镁显著高于对照者，而总镁无差异。糖尿病患者和对照者的血清离子镁与总镁相关。总镁与Hb A1c呈负相关；离子镁与Hb A1c之间的相关性无统计学意义。
我们的数据不支持2型糖尿病患者常规补充或监测镁。
