来自一种海洋真菌的新型聚酮化合物代谢产物。

Novel polyketide metabolites from a species of marine fungi.

作者信息

Smith C J, Abbanat D, Bernan V S, Maiese W M, Greenstein M, Jompa J, Tahir A, Ireland C M

机构信息

Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84112, USA.

出版信息

J Nat Prod. 2000 Jan;63(1):142-5. doi: 10.1021/np990361w.

DOI:10.1021/np990361w

PMID:10650098

Abstract

Fermentation of a marine fungal species obtained from a tissue sample of a marine sponge collected in Indonesia in October 1996, yielded the novel hexaketide compounds iso-cladospolide B (1); seco-patulolide C (2); the 12-membered macrolides, pandangolide 1 (3) and pandangolide 2 (4); and the known terrestrial fungal metabolite, cladospolide B (5).

摘要

对1996年10月在印度尼西亚采集的海洋海绵组织样本中获得的一种海洋真菌进行发酵，得到了新型六酮化合物异枝盘孢菌素B（1）；裂环帕图洛内酯C（2）；12元大环内酯类化合物盘东醇1（3）和盘东醇2（4）；以及已知的陆生真菌代谢产物枝盘孢菌素B（5）。