Alexander E L, Wetzel B
Science. 1975 May 16;188(4189):732-4. doi: 10.1126/science.1079095.
When viewed by scanning electron microscopy human lymphocytes fixed in suspension and processed with minimal cell loss appear uniformly covered with short microvilli. Contrary to previous reports, lymphocytes from subpopulations selectively enriched for T cells are villous and indistinguishable from B lymphocytes. Whereas lymphocyte surface architecture can change rapidly and substantially in response to environmental modifications, such as contact with an underlying surface, these alterations are similar for both B and T cells and do not serve to distinguish these subpopulations.
通过扫描电子显微镜观察，固定在悬浮液中并以最小细胞损失进行处理的人类淋巴细胞似乎均匀地覆盖着短微绒毛。与先前的报道相反，选择性富集T细胞的亚群中的淋巴细胞有绒毛，与B淋巴细胞无法区分。尽管淋巴细胞表面结构可因环境改变（如与下层表面接触）而迅速且显著变化，但B细胞和T细胞的这些改变相似，无法用于区分这些亚群。
