Whittaker J C, Thompson R, Denham M C
Department of Applied Statistics, University of Reading, UK.
Genet Res. 2000 Apr;75(2):249-52. doi: 10.1017/s0016672399004462.
In cross between inbred lines, linear regression can be used to estimate the correlation of markers with a trait of interest; these marker effects then allow marker assisted selection (MAS) for quantitative traits. Usually a subset of markers to include in the model must be selected: no completely satisfactory method of doing this exists. We show that replacing this selection of markers by ridge regression can improve the mean response to selection and reduce the variability of selection response.
在近交系之间的杂交中,线性回归可用于估计标记与感兴趣性状之间的相关性;这些标记效应随后可用于数量性状的标记辅助选择(MAS)。通常必须选择模型中要包含的标记子集:目前尚无完全令人满意的方法来做到这一点。我们表明,用岭回归代替这种标记选择可以提高选择的平均响应,并降低选择响应的变异性。