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人类淋巴细胞亚群中的溶酶体酸性水解酶。

Lysosomal acid hydrolases in human lymphocyte subpopulations.

作者信息

Barr R D, Perry S

出版信息

Br J Haematol. 1976 Apr;32(4):565-72. doi: 10.1111/j.1365-2141.1976.tb00960.x.

DOI:10.1111/j.1365-2141.1976.tb00960.x
PMID:1083246
Abstract

Acid phosphatase and beta-glucuronidase activities have been determined cytochemically in T, B and null lymphocytes as part of an effort to charaterize the human haemopoietic stem cell. A combination of weak acid phosphatase activity and strong beta glucuronidase staining, in the form of a single large granule, has been shown to be specific for T cells. On the basis of this approach alone, non-T cells could not be further subclassified. Further cytochemical evaluation is being explored.

摘要

作为表征人类造血干细胞工作的一部分,已通过细胞化学方法测定了T、B和裸淋巴细胞中的酸性磷酸酶和β-葡萄糖醛酸酶活性。已证明,以单个大颗粒形式存在的弱酸磷酸酶活性和强β-葡萄糖醛酸酶染色的组合是T细胞特有的。仅基于这种方法,非T细胞无法进一步细分。正在探索进一步的细胞化学评估。

相似文献

1
Lysosomal acid hydrolases in human lymphocyte subpopulations.人类淋巴细胞亚群中的溶酶体酸性水解酶。
Br J Haematol. 1976 Apr;32(4):565-72. doi: 10.1111/j.1365-2141.1976.tb00960.x.
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[Lysosomal enzymes in lymphocytes. I. Lymphoreticular diseases: comparison of the enzyme content (acid phosphatase, beta-glucuronidase) in unstimulated lymphocytes with blastic transformation after stimulation with phytohemagglutinin beta-Glucuronidase in vitro].淋巴细胞中的溶酶体酶。I. 淋巴网状系统疾病:体外经植物血凝素刺激后发生原始细胞转化的未刺激淋巴细胞中酶含量(酸性磷酸酶、β-葡萄糖醛酸酶)的比较]
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引用本文的文献

1
Morphological aspects of T cell subpopulations in human blood: characterization of the cerebriform mononuclear cells in healthy individuals.人血中T细胞亚群的形态学特征:健康个体中脑形单核细胞的特性
Clin Exp Immunol. 1981 Mar;43(3):506-16.
2
Ultrastructural localization of acid phosphatase in rosetted T and B lymphocytes of normal human blood.正常人血中玫瑰花结形成的T淋巴细胞和B淋巴细胞酸性磷酸酶的超微结构定位
Am J Pathol. 1981 Jan;102(1):72-83.
3
Cytochemical comparison of immunologically characterized human leukaemia/lymphoma cell lines representing different levels of maturation.
代表不同成熟水平的经免疫特征化的人白血病/淋巴瘤细胞系的细胞化学比较。
Br J Cancer. 1983 Jun;47(6):771-9. doi: 10.1038/bjc.1983.130.
4
Ultrastructural localization of a lysosomal enzyme in resin-embedded lymphocytes.树脂包埋淋巴细胞中溶酶体酶的超微结构定位
Histochemistry. 1988;89(1):69-74. doi: 10.1007/BF00496587.
5
Ultrastructural studies of a lysosomal enzyme during lymphocyte activation.淋巴细胞激活过程中一种溶酶体酶的超微结构研究。
Br J Exp Pathol. 1988 Oct;69(5):661-70.
6
Cathepsin D activity in human peripheral blood mononuclear leukocytes.人外周血单个核白细胞中的组织蛋白酶D活性
Inflammation. 1989 Jun;13(3):309-16. doi: 10.1007/BF00914397.
7
Malignant lymphomas--a conceptual understanding of morphologic diversity. A review.恶性淋巴瘤——对形态学多样性的概念性理解。综述。
Am J Pathol. 1979 Jan;94(1):105-92.
8
Enzyme differentiation of lymphocyte subpopulations in sections of human lymph nodes, tonsils and periodontal disease.人淋巴结、扁桃体切片及牙周病中淋巴细胞亚群的酶分化
Clin Exp Immunol. 1978 Apr;32(1):169-78.
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Comparison of enzyme-cytochemical findings and immunological marker investigations in acute lymphatic leukemia (ALL).急性淋巴细胞白血病(ALL)中酶细胞化学结果与免疫标志物检测的比较。
Blut. 1978 May 18;36(5):299-305. doi: 10.1007/BF01880680.
10
Cytochemical identification of human T-lymphocytes.人T淋巴细胞的细胞化学鉴定
Can Med Assoc J. 1978 May 20;118(10):1279-80, 1285.