兔肠道黏膜淋巴细胞中的功能性T细胞。
Functional T cells in rabbits gut mucosal lymphocytes.
作者信息
Singal D P, O'Neill M, Clancy R, Bienenstock J
出版信息
Gut. 1976 May;17(5):325-7. doi: 10.1136/gut.17.5.325.
Abstract
Functional studies of Peyer's patch and gut mucosa lymphocytes were performed in mixed lymphocyte culture reaction (MLC), an in vitro measure of the capacity of T cells to recognize and respond to cell surface alloantigens. The data demonstrate the functional effectiveness of both these mucosal lymphocyte populations in one-way MLC, both as responding as well as stimulating cells. Both the responding and stimulating capacities of these cells in MLC were almost the same as observed for lymphocytes obtained from either spleen or thymus. We conclude that functional T cells exist in both rabbit gut lamina propria and Peyer's patches with approximately the same quantitative capacity to respond in the MLC.
摘要
在混合淋巴细胞培养反应（MLC）中对派尔集合淋巴结和肠道黏膜淋巴细胞进行了功能研究，MLC是一种体外检测T细胞识别和应答细胞表面同种异体抗原能力的方法。数据表明，在单向MLC中，这两种黏膜淋巴细胞群体作为应答细胞和刺激细胞均具有功能有效性。这些细胞在MLC中的应答和刺激能力与从脾脏或胸腺获得的淋巴细胞所观察到的几乎相同。我们得出结论，兔肠道固有层和派尔集合淋巴结中均存在功能性T细胞，它们在MLC中的应答定量能力大致相同。
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Suppression of immunoglobulin G synthesis as a result of antibody-mediated suppression of immunoglobulin M synthesis in chickens.抗体介导抑制鸡免疫球蛋白M合成导致免疫球蛋白G合成受抑制。
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