Vu H D, Heller R F, Lim L L, D'Este C, O'Connell R L
Centre for Clinical Epidemiology and Biostatistics, The University of Newcastle, David Maddison Clinical Sciences Building, Royal Newcastle Hospital, Newcastle NSW 2300, Australia.
J Epidemiol Community Health. 2000 Aug;54(8):590-5. doi: 10.1136/jech.54.8.590.
To compare in-hospital mortality for acute myocardial infarction (AMI) between metropolitan and non-metropolitan hospitals after adjustment for patients' severity; to examine the role of the use of effective cardiac medications in the possible mortality difference between these types of hospital.
Retrospective cohort study.
47 acute public hospitals in metropolitan and non-metropolitan areas of New South Wales, Australia, taking part in the Acute Cardiac Care Project based on medical record review.
1665 patients with principal discharge diagnosis of AMI from February to June 1996.
There was no difference in crude mortality rate (assessed as seven day mortality) between metropolitan and non-metropolitan hospitals (11.0% compared with 10.7% respectively, p=0.893). After adjustment for severity in a logistic regression model, the odds of death in non-metropolitan hospitals was significantly higher than in metropolitan hospitals (odds ratio = 1. 90; 95% CI 1.21, 3.23). The addition of the use of effective cardiac medications to the model resulted in the difference between hospital type becoming non-significant (odds ratio=1.09; 95% CI 0.57, 2.07).
In-hospital mortality in non-metropolitan hospitals was higher than that in metropolitan hospitals, after adjustment for patients' severity. This might partly be explained by the difference in use of effective cardiac medications between hospital type.
在对患者病情严重程度进行校正后,比较大城市医院和非大城市医院急性心肌梗死(AMI)患者的院内死亡率;探讨有效心脏药物的使用在这两类医院可能存在的死亡率差异中所起的作用。
回顾性队列研究。
澳大利亚新南威尔士州大城市和非大城市地区的47家急性公立医院,基于病历审查参与急性心脏护理项目。
1996年2月至6月主要出院诊断为AMI的1665例患者。
大城市医院和非大城市医院的粗死亡率(以七天死亡率评估)无差异(分别为11.0%和10.7%,p = 0.893)。在逻辑回归模型中对病情严重程度进行校正后,非大城市医院的死亡几率显著高于大城市医院(优势比 = 1.90;95%可信区间1.21, 3.23)。在模型中加入有效心脏药物的使用情况后,医院类型之间的差异变得不显著(优势比 = 1.09;95%可信区间0.57, 2.07)。
在对患者病情严重程度进行校正后,非大城市医院的院内死亡率高于大城市医院。这可能部分是由于不同类型医院在有效心脏药物使用上的差异所致。