来自皮氏罗尔斯通氏菌（假单胞菌属）的染色体诱导型D类β-内酰胺酶OXA-22的生化遗传学特征及分布
Biochemical-genetic characterization and distribution of OXA-22, a chromosomal and inducible class D beta-lactamase from Ralstonia (Pseudomonas) pickettii.
作者信息
Nordmann P, Poirel L, Kubina M, Casetta A, Naas T
机构信息
Service de Bactériologie-Virologie, Hôpital de Bicêtre, Assistance Publique/Hôpitaux de Paris, Faculté de Médecine Paris-Sud, 94275 Le Kremlin-Bicêtre, France.
出版信息
Antimicrob Agents Chemother. 2000 Aug;44(8):2201-4. doi: 10.1128/AAC.44.8.2201-2204.2000.
Abstract
From genomic DNA of Ralstonia pickettii isolate PIC-1, a beta-lactamase gene was cloned that encodes the oxacillinase OXA-22. It differs from known oxacillinases, being most closely related to OXA-9 (38% amino acid identity). The hydrolytic spectrum of OXA-22 is limited mostly to benzylpenicillin, cloxacillin, and restricted-spectrum cephalosporins. OXA-22-like genes were identified as single chromosomal copies in five other R. pickettii clinical isolates. The expression of OXA-22-like beta-lactamases was inducible in R. pickettii.
摘要
从皮氏罗尔斯通氏菌分离株PIC-1的基因组DNA中克隆到一个编码奥沙西林酶OXA-22的β-内酰胺酶基因。它与已知的奥沙西林酶不同，与OXA-9的关系最为密切（氨基酸同一性为38%）。OXA-22的水解谱主要限于苄青霉素、氯唑西林和窄谱头孢菌素。在其他5株皮氏罗尔斯通氏菌临床分离株中，OXA-22样基因被鉴定为单染色体拷贝。OXA-22样β-内酰胺酶在皮氏罗尔斯通氏菌中可诱导表达。
相似文献
1
Biochemical-genetic characterization and distribution of OXA-22, a chromosomal and inducible class D beta-lactamase from Ralstonia (Pseudomonas) pickettii.来自皮氏罗尔斯通氏菌（假单胞菌属）的染色体诱导型D类β-内酰胺酶OXA-22的生化遗传学特征及分布
Antimicrob Agents Chemother. 2000 Aug;44(8):2201-4. doi: 10.1128/AAC.44.8.2201-2204.2000.
2
OXA-60, a chromosomal, inducible, and imipenem-hydrolyzing class D beta-lactamase from Ralstonia pickettii.OXA-60，一种来自皮氏罗尔斯通氏菌的染色体介导的、可诱导的、能水解亚胺培南的D类β-内酰胺酶。
Antimicrob Agents Chemother. 2004 Nov;48(11):4217-25. doi: 10.1128/AAC.48.11.4217-4225.2004.
3
Regulation of class D beta-lactamase gene expression in Ralstonia pickettii.
Microbiology (Reading). 2006 Sep;152(Pt 9):2661-2672. doi: 10.1099/mic.0.29027-0.
4
OXA-18, a class D clavulanic acid-inhibited extended-spectrum beta-lactamase from Pseudomonas aeruginosa.OXA-18，一种来自铜绿假单胞菌的D类克拉维酸抑制型超广谱β-内酰胺酶。
Antimicrob Agents Chemother. 1997 Oct;41(10):2188-95. doi: 10.1128/AAC.41.10.2188.
5
Molecular characterization of OXA-20, a novel class D beta-lactamase, and its integron from Pseudomonas aeruginosa.新型D类β-内酰胺酶OXA-20及其来自铜绿假单胞菌的整合子的分子特征
Antimicrob Agents Chemother. 1998 Aug;42(8):2074-83. doi: 10.1128/AAC.42.8.2074.
6
OXA-35 is an OXA-10-related beta-lactamase from Pseudomonas aeruginosa.OXA-35是一种来自铜绿假单胞菌的与OXA-10相关的β-内酰胺酶。
J Antimicrob Chemother. 2001 Nov;48(5):717-21. doi: 10.1093/jac/48.5.717.
7
Cloning and expression of a cloxacillin-hydrolyzing enzyme and a cephalosporinase from Aeromonas sobria AER 14M in Escherichia coli: requirement for an E. coli chromosomal mutation for efficient expression of the class D enzyme.嗜水气单胞菌AER 14M中一种氯唑西林水解酶和一种头孢菌素酶在大肠杆菌中的克隆与表达：D类酶高效表达对大肠杆菌染色体突变的需求
Antimicrob Agents Chemother. 1994 Sep;38(9):2078-85. doi: 10.1128/AAC.38.9.2078.
8
Characterization of a naturally occurring class D beta-lactamase from Achromobacter xylosoxidans.木糖氧化无色杆菌天然存在的D类β-内酰胺酶的特性分析
Antimicrob Agents Chemother. 2008 Jun;52(6):1952-6. doi: 10.1128/AAC.01463-07. Epub 2008 Mar 24.
9
Biochemical-genetic characterization of the chromosomally encoded extended-spectrum class A beta-lactamase from Rahnella aquatilis.水生拉恩菌染色体编码的超广谱A类β-内酰胺酶的生化遗传学特性
Antimicrob Agents Chemother. 2001 Oct;45(10):2965-8. doi: 10.1128/AAC.45.10.2965-2968.2001.
10
Molecular and biochemical characterization of the natural chromosome-encoded class A beta-lactamase from Pseudomonas luteola.从黄假单胞菌中天然染色体编码的 A 类β-内酰胺酶的分子和生化特性分析。
Antimicrob Agents Chemother. 2010 Jan;54(1):45-51. doi: 10.1128/AAC.00427-09. Epub 2009 Nov 2.
引用本文的文献
1
Oropharyngeal resistome remains stable during COVID-19 therapy, while fecal resistome shifts toward a less diverse resistotype.在新冠病毒疾病治疗期间，口咽耐药基因组保持稳定，而粪便耐药基因组则向多样性较低的耐药型转变。
iScience. 2024 Nov 5;27(12):111319. doi: 10.1016/j.isci.2024.111319. eCollection 2024 Dec 20.
2
Novel species from human infections: improved matrix-assisted laser desorption/ionization time-of-flight mass spectrometry-based identification and analysis of antimicrobial resistance patterns.从人类感染中分离出新的物种：基于基质辅助激光解吸/电离飞行时间质谱的改进方法鉴定和分析抗生素耐药模式。
Microbiol Spectr. 2024 Jun 4;12(6):e0402123. doi: 10.1128/spectrum.04021-23. Epub 2024 Apr 25.
3
Genomic analysis of reveals the genetic features for potential pathogenicity and adaptive evolution in drinking water.对……的基因组分析揭示了饮用水中潜在致病性和适应性进化的遗传特征。
注：原文中“Genomic analysis of ”后面缺少具体内容。
Front Microbiol. 2024 Feb 2;14:1272636. doi: 10.3389/fmicb.2023.1272636. eCollection 2023.
4
Comparative Genomics Identified PenR E151V Substitution Associated with Carbapenem-Resistance Complex and a Novel Complex Specific OXA-1043 Subgroup.比较基因组学鉴定出与碳青霉烯耐药复合体相关的PenR E151V替换以及一个新型的复合体特异性OXA-1043亚组。
Infect Drug Resist. 2023 Aug 28;16:5627-5635. doi: 10.2147/IDR.S418969. eCollection 2023.
5
Characterization of clinical Ralstonia strains and their taxonomic position.临床罗尔斯通氏菌菌株的特征及其分类地位。
Antonie Van Leeuwenhoek. 2021 Oct;114(10):1721-1733. doi: 10.1007/s10482-021-01637-0. Epub 2021 Aug 31.
6
Longitudinal changes in the nasopharyngeal resistome of South African infants using shotgun metagenomic sequencing.南非婴儿鼻咽部耐药组的纵向变化：采用鸟枪法宏基因组测序研究。
PLoS One. 2020 Apr 22;15(4):e0231887. doi: 10.1371/journal.pone.0231887. eCollection 2020.
7
infections in an oncologic day ward: description of a cluster among high-risk patients.肿瘤日间病房的感染：高危患者群体的描述
Antimicrob Resist Infect Control. 2017 Feb 7;6:20. doi: 10.1186/s13756-017-0178-z. eCollection 2017.
8
CTX-M extended-spectrum β-lactamase-producing Klebsiella spp, Salmonella spp, Shigella spp and Escherichia coli isolates in Iranian hospitals.伊朗医院中产CTX-M型超广谱β-内酰胺酶的克雷伯菌属、沙门菌属、志贺菌属和大肠杆菌分离株
Braz J Microbiol. 2016 Jul-Sep;47(3):706-11. doi: 10.1016/j.bjm.2016.04.020. Epub 2016 Apr 22.
9
Genome Sequence of a Carbapenem-Resistant Strain of Ralstonia mannitolilytica.一株耐碳青霉烯类的嗜麦芽窄食单胞菌的基因组序列
Genome Announc. 2015 May 7;3(3):e00405-15. doi: 10.1128/genomeA.00405-15.
10
Ralstonia spp.: emerging global opportunistic pathogens.嗜麦芽窄食单胞菌属：新兴的全球机会致病菌
Eur J Clin Microbiol Infect Dis. 2014 Mar;33(3):291-304. doi: 10.1007/s10096-013-1975-9. Epub 2013 Sep 21.
本文引用的文献
1
Genetic-biochemical analysis and distribution of the Ambler class A beta-lactamase CME-2, responsible for extended-spectrum cephalosporin resistance in Chryseobacterium (Flavobacterium) meningosepticum.负责脑膜炎败血金黄杆菌（黄杆菌属）中对超广谱头孢菌素耐药的安布勒A类β-内酰胺酶CME-2的遗传生化分析及分布情况
Antimicrob Agents Chemother. 2000 Jan;44(1):1-9. doi: 10.1128/AAC.44.1.1-9.2000.
2
OXA-type beta-lactamases.OXA型β-内酰胺酶
Curr Pharm Des. 1999 Nov;5(11):865-79.
3
Integron- and carbenicillinase-mediated reduced susceptibility to amoxicillin-clavulanic acid in isolates of multidrug-resistant Salmonella enterica serotype typhimurium DT104 from French patients.来自法国患者的多重耐药鼠伤寒沙门氏菌血清型DT104分离株中整合子和羧苄青霉素酶介导的对阿莫西林-克拉维酸敏感性降低
Antimicrob Agents Chemother. 1999 May;43(5):1098-104. doi: 10.1128/AAC.43.5.1098.
4
Cloning, sequence analyses, expression, and distribution of ampC-ampR from Morganella morganii clinical isolates.摩根氏摩根菌临床分离株中AmpC - AmpR的克隆、序列分析、表达及分布
Antimicrob Agents Chemother. 1999 Apr;43(4):769-76. doi: 10.1128/AAC.43.4.769.
5
Molecular characterization of OXA-20, a novel class D beta-lactamase, and its integron from Pseudomonas aeruginosa.新型D类β-内酰胺酶OXA-20及其来自铜绿假单胞菌的整合子的分子特征
Antimicrob Agents Chemother. 1998 Aug;42(8):2074-83. doi: 10.1128/AAC.42.8.2074.
6
OXA-18, a class D clavulanic acid-inhibited extended-spectrum beta-lactamase from Pseudomonas aeruginosa.OXA-18，一种来自铜绿假单胞菌的D类克拉维酸抑制型超广谱β-内酰胺酶。
Antimicrob Agents Chemother. 1997 Oct;41(10):2188-95. doi: 10.1128/AAC.41.10.2188.
7
Comparison of biotyping, ribotyping, and pulsed-field gel electrophoresis for investigation of a common-source outbreak of Burkholderia pickettii bacteremia.生物分型、核糖体分型和脉冲场凝胶电泳用于调查皮氏伯克霍尔德菌菌血症共同来源暴发的比较
J Clin Microbiol. 1997 Jun;35(6):1398-403. doi: 10.1128/jcm.35.6.1398-1403.1997.
8
Antibacterial activity of BMS-180680, a new catechol-containing monobactam.新型含儿茶酚单环β-内酰胺类抗生素BMS-180680的抗菌活性
Antimicrob Agents Chemother. 1997 May;41(5):1010-6. doi: 10.1128/AAC.41.5.1010.
9
Expression of the AsbA1, OXA-12, and AsbM1 beta-lactamases in Aeromonas jandaei AER 14 is coordinated by a two-component regulon.詹氏气单胞菌AER 14中AsbA1、OXA - 12和AsbM1β-内酰胺酶的表达由一个双组分调节子调控。
J Bacteriol. 1997 Mar;179(6):2006-13. doi: 10.1128/jb.179.6.2006-2013.1997.
10
Transfer of two Burkholderia and an Alcaligenes species to Ralstonia gen. Nov.: Proposal of Ralstonia pickettii (Ralston, Palleroni and Doudoroff 1973) comb. Nov., Ralstonia solanacearum (Smith 1896) comb. Nov. and Ralstonia eutropha (Davis 1969) comb. Nov.将两种伯克霍尔德菌属和一种产碱菌属细菌转移至罗尔斯通氏菌属新属：罗尔斯通氏菌皮氏亚种（Ralston、Palleroni和Doudoroff，1973年）新组合、罗尔斯通氏菌青枯亚种（Smith，1896年）新组合和罗尔斯通氏菌真养亚种（Davis，1969年）新组合的提议
Microbiol Immunol. 1995;39(11):897-904. doi: 10.1111/j.1348-0421.1995.tb03275.x.
Zotero 插件