巨噬细胞在短小棒状杆菌对抗体产生的佐剂效应中的作用。
The role of macrophages in the adjuvant effect on antibody production of Corynebacterium parvum.
作者信息
Watson S R, Sljivić V S
出版信息
Clin Exp Immunol. 1976 Jan;23(1):149-53.
Abstract
Spleen cells from mice pre-treated with C. parvum gave an enhanced in vitro antibody response to SRBC, but not to DNP-POL. This enhancing activity was associated with the adherent, but not the non-adherent spleen cell population and was found to be radioresistant. It is concluded that macrophages are directly involved in the adjuvant effect of C. parvum and the possible mechanisms of action are discussed.
摘要
用微小隐孢子虫预处理的小鼠脾细胞对绵羊红细胞的体外抗体反应增强，但对二硝基苯-多聚赖氨酸则不然。这种增强活性与贴壁脾细胞群体有关，而非非贴壁脾细胞群体，并且发现具有抗辐射性。得出的结论是巨噬细胞直接参与微小隐孢子虫的佐剂效应，并讨论了可能的作用机制。
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