• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

大肠杆菌的3-磷酸甘油醛脱氢酶突变体

Glyceraldehyde 3-phosphate dehydrogenase mutants of Escherichia coli.

作者信息

Hillman J D, Fraenkel D G

出版信息

J Bacteriol. 1975 Jun;122(3):1175-9. doi: 10.1128/jb.122.3.1175-1179.1975.

DOI:10.1128/jb.122.3.1175-1179.1975
PMID:1097392
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC246174/
Abstract

We describe glyceraldehyde 3-phosphate dehydrogenase mutants of Escherichia coli. The gene (gap) is at approximately 34 min, with the transductional order gap-fadD-eda. One gap mutant is temperature sensitive and has a heat-labile enzyme. Another is amber.

摘要

我们描述了大肠杆菌的3-磷酸甘油醛脱氢酶突变体。该基因(gap)位于约34分钟处,转导顺序为gap-fadD-eda。一个gap突变体对温度敏感,其酶对热不稳定。另一个是琥珀型突变体。

相似文献

1
Glyceraldehyde 3-phosphate dehydrogenase mutants of Escherichia coli.大肠杆菌的3-磷酸甘油醛脱氢酶突变体
J Bacteriol. 1975 Jun;122(3):1175-9. doi: 10.1128/jb.122.3.1175-1179.1975.
2
Glyceraldehyde 3-p dehydrogenase, glycerate 3-P kinase and enolase mutants of Escherichia coli: genetic studies.
Mol Gen Genet. 1976 Apr 23;145(1):65-71. doi: 10.1007/BF00331559.
3
Mutants of Escherichia coli defective in membrane phospholipid synthesis: mapping of the structural gene for L-glycerol 3-phosphate dehydrogenase.膜磷脂合成存在缺陷的大肠杆菌突变体:L-甘油-3-磷酸脱氢酶结构基因的定位
J Bacteriol. 1974 May;118(2):598-605. doi: 10.1128/jb.118.2.598-605.1974.
4
Regulation of beta-glucuronidase synthesis in Escherichia coli K-12: constitutive mutants specifically derepressed for uidA expression.大肠杆菌K-12中β-葡萄糖醛酸酶合成的调控:uidA表达特异性去阻遏的组成型突变体。
J Bacteriol. 1976 Jul;127(1):406-17. doi: 10.1128/jb.127.1.406-417.1976.
5
Molecular cloning of the glyceraldehyde-3-phosphate dehydrogenase genes of Bacillus stearothermophilus and Escherichia coli, and their expression in Escherichia coli.嗜热脂肪芽孢杆菌和大肠杆菌3-磷酸甘油醛脱氢酶基因的分子克隆及其在大肠杆菌中的表达。
Gene. 1983 Nov;25(1):1-7. doi: 10.1016/0378-1119(83)90161-0.
6
Mutations affecting transport of the hexitols D-mannitol, D-glucitol, and galactitol in Escherichia coli K-12: isolation and mapping.影响大肠杆菌K-12中己糖醇D-甘露醇、D-葡萄糖醇和半乳糖醇转运的突变:分离与定位
J Bacteriol. 1975 Oct;124(1):26-38. doi: 10.1128/jb.124.1.26-38.1975.
7
Isolation and characterization of Escherichia coli mutants defective in enzymes of glycolysis.糖酵解酶缺陷型大肠杆菌突变体的分离与鉴定。
Biochem Biophys Res Commun. 1974 Jan;56(1):127-33. doi: 10.1016/s0006-291x(74)80324-4.
8
Glutamate dehydrogenase: genetic mapping and isolation of regulatory mutants of Klebsiella aerogenes.谷氨酸脱氢酶:产气克雷伯菌的遗传图谱绘制及调控突变体的分离
J Bacteriol. 1976 Jul;127(1):141-8. doi: 10.1128/jb.127.1.141-148.1976.
9
Mutant analysis of glyceraldehyde 3-phosphate dehydrogenase in Escherichia coli.大肠杆菌中3-磷酸甘油醛脱氢酶的突变分析
Biochem J. 1979 Apr 1;179(1):99-107. doi: 10.1042/bj1790099.
10
Genetic mapping of loci for glucose-6-phosphate dehydrogenase, gluconate-6-phosphate dehydrogenase, and gluconate-6-phosphate dehydrase in Escherichia coli.大肠杆菌中葡萄糖-6-磷酸脱氢酶、6-磷酸葡萄糖酸脱氢酶和6-磷酸葡萄糖酸脱水酶基因座的遗传定位
J Bacteriol. 1968 Apr;95(4):1272-8. doi: 10.1128/jb.95.4.1272-1278.1968.

引用本文的文献

1
CRISPRi-based programmable logic inverter cascade for antibiotic-free selection and maintenance of multiple plasmids.基于 CRISPRi 的可编程逻辑反相器级联,用于无抗生素选择和维持多个质粒。
Nucleic Acids Res. 2022 Dec 9;50(22):13155-13171. doi: 10.1093/nar/gkac1104.
2
Enhancement of 3-hydroxypropionic acid production from glycerol by using a metabolic toggle switch.利用代谢切换开关提高甘油生产3-羟基丙酸的产量
Microb Cell Fact. 2015 Oct 5;14:155. doi: 10.1186/s12934-015-0342-1.
3
A genome-scale metabolic flux model of Escherichia coli K-12 derived from the EcoCyc database.一个源自EcoCyc数据库的大肠杆菌K-12全基因组规模代谢通量模型。
BMC Syst Biol. 2014 Jun 30;8:79. doi: 10.1186/1752-0509-8-79.
4
Improvement of NADPH bioavailability in Escherichia coli by replacing NAD(+)-dependent glyceraldehyde-3-phosphate dehydrogenase GapA with NADP (+)-dependent GapB from Bacillus subtilis and addition of NAD kinase.通过用枯草芽孢杆菌 NADP(+)依赖型 3-磷酸甘油醛脱氢酶 GapB 替代依赖 NAD(+)的甘油醛-3-磷酸脱氢酶 GapA,并添加 NAD 激酶,提高大肠杆菌中 NADPH 的生物利用度。
J Ind Microbiol Biotechnol. 2013 Dec;40(12):1449-60. doi: 10.1007/s10295-013-1335-x. Epub 2013 Sep 19.
5
In silico identification of gene amplification targets for improvement of lycopene production.通过计算机筛选确定基因扩增靶点,提高番茄红素产量。
Appl Environ Microbiol. 2010 May;76(10):3097-105. doi: 10.1128/AEM.00115-10. Epub 2010 Mar 26.
6
Inhibition of cell surface export of group A streptococcal anchorless surface dehydrogenase affects bacterial adherence and antiphagocytic properties.A群链球菌无锚定表面脱氢酶细胞表面输出的抑制影响细菌黏附及抗吞噬特性。
Infect Immun. 2005 Oct;73(10):6237-48. doi: 10.1128/IAI.73.10.6237-6248.2005.
7
Global analysis of Escherichia coli RNA degradosome function using DNA microarrays.利用DNA微阵列对大肠杆菌RNA降解体功能进行全局分析。
Proc Natl Acad Sci U S A. 2004 Mar 2;101(9):2758-63. doi: 10.1073/pnas.0308747101. Epub 2004 Feb 23.
8
Analysis of protein synthesis rates after initiation of chromosome replication in Escherichia coli.大肠杆菌染色体复制起始后蛋白质合成速率的分析
J Bacteriol. 1999 Oct;181(20):6292-9. doi: 10.1128/JB.181.20.6292-6299.1999.
9
The EIIGlc protein is involved in glucose-mediated activation of Escherichia coli gapA and gapB-pgk transcription.EIIGlc蛋白参与葡萄糖介导的大肠杆菌gapA和gapB - pgk转录激活过程。
J Bacteriol. 1998 Dec;180(24):6476-83. doi: 10.1128/JB.180.24.6476-6483.1998.
10
Involvement of the gapA- and epd (gapB)-encoded dehydrogenases in pyridoxal 5'-phosphate coenzyme biosynthesis in Escherichia coli K-12.大肠杆菌K-12中由gapA和epd(gapB)编码的脱氢酶参与磷酸吡哆醛辅酶生物合成
J Bacteriol. 1998 Aug;180(16):4294-9. doi: 10.1128/JB.180.16.4294-4299.1998.

本文引用的文献

1
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
2
PROTEIN AND NUCLEIC ACID SYNTHESIS IN TWO MUTANTS OF ESCHERICHIA COLI WITH TEMPERATURE-SENSITIVE AMINOACYL RIBONUCLEIC ACID SYNTHETASES.具有温度敏感型氨酰核糖核酸合成酶的大肠杆菌两个突变体中的蛋白质和核酸合成
J Bacteriol. 1965 Mar;89(3):706-11. doi: 10.1128/jb.89.3.706-711.1965.
3
A kinetic study of glycolytic enzyme synthesis in yeast.酵母中糖酵解酶合成的动力学研究。
J Biol Chem. 1971 Jan 25;246(2):475-88.
4
Glucose and gluconate metabolism in an Escherichia coli mutant lacking phosphoglucose isomerase.缺乏磷酸葡萄糖异构酶的大肠杆菌突变体中的葡萄糖和葡萄糖酸盐代谢
J Bacteriol. 1967 May;93(5):1571-8. doi: 10.1128/jb.93.5.1571-1578.1967.
5
2-keto-3-deoxygluconate 6-phosphate aldolase mutants of Escherichia coli.大肠杆菌的2-酮-3-脱氧葡萄糖酸6-磷酸醛缩酶突变体
J Bacteriol. 1971 Dec;108(3):1277-83. doi: 10.1128/jb.108.3.1277-1283.1971.
6
[Map location of 2-keto-3-deoxy-6-P-gluconate aldolase negative mutations in E. coli K12].[大肠杆菌K12中2-酮-3-脱氧-6-磷酸葡萄糖酸醛缩酶阴性突变的图谱定位]
Mol Gen Genet. 1971;113(1):31-42.
7
Glyceraldehyde phosphate dehydrogenase, phosphoglycerate kinase, and phosphoglyceromutase of Escherichia coli. Simultaneous purification and physical properties.大肠杆菌的磷酸甘油醛脱氢酶、磷酸甘油酸激酶和磷酸甘油变位酶。同步纯化及物理性质
J Biol Chem. 1971 Jul 10;246(13):4319-25.
8
Induction of closely linked multiple mutations by nitrosoguanidine.亚硝基胍诱导紧密连锁的多重突变
Nat New Biol. 1971 Mar 24;230(12):122-5. doi: 10.1038/newbio230122a0.
9
Transketolase mutants of Escherichia coli.大肠杆菌的转酮醇酶突变体
J Bacteriol. 1969 Dec;100(3):1289-95. doi: 10.1128/jb.100.3.1289-1295.1969.
10
Fatty acid degradation in Escherichia coli. An inducible acyl-CoA synthetase, the mapping of old-mutations, and the isolation of regulatory mutants.大肠杆菌中的脂肪酸降解。一种可诱导的酰基辅酶A合成酶、旧突变的定位以及调节突变体的分离。
Eur J Biochem. 1969 Feb;7(4):559-74.