产气肠杆菌染色体ampC基因的核苷酸序列。
Nucleotide sequence of the chromosomal ampC gene of Enterobacter aerogenes.
作者信息
Preston K E, Radomski C C, Venezia R A
机构信息
Department of Pathology and Laboratory Medicine, Albany Medical Center Hospital, Albany, New York 12208, USA.
出版信息
Antimicrob Agents Chemother. 2000 Nov;44(11):3158-62. doi: 10.1128/AAC.44.11.3158-3162.2000.
Abstract
The AmpC beta-lactamase gene and a small portion of the regulatory ampR sequence of Enterobacter aerogenes 97B were cloned and sequenced. The beta-lactamase had an isoelectric point of 8 and conferred cephalosporin and cephamycin resistance on the host. The sequence of the cloned gene is most closely related to those of the ampC genes of E. cloacae and C. freundii.
摘要
对产气肠杆菌97B的AmpCβ-内酰胺酶基因和一小部分调控ampR序列进行了克隆和测序。该β-内酰胺酶的等电点为8，并赋予宿主对头孢菌素和头霉素的抗性。克隆基因的序列与阴沟肠杆菌和弗氏柠檬酸杆菌的ampC基因序列关系最为密切。
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