Duboucher C, Farto-Bensasson F, Chéron M, Peltier J Y, Beaufils F, Périé G
Department of Pathology, Saint-Germain-en-Laye Hospital, France.
Hum Pathol. 2000 Oct;31(10):1317-21. doi: 10.1053/hupa.2000.18502.
In an 82-year-old woman, presenting with fever and asthenia, cervical adenopathy was noted. Clinical and radiological investigations were fruitless. Laboratory examinations detected a refractory anemia. The lymph node was excised and showed numerous trichomonads on touch preparations. Histologically, the node showed caseous necrosis and macrophagic reaction. Diagnosis of lymph node infection by Trichomonas tenax was made. Three weeks later, culture of the node showed Mycobacterium tuberculosis and let us conclude co-infection. T tenax is usually regarded as a harmless saprophyte of the oral cavity. This exceptional observation shows for the first time an invasive potential of T tenax. It raises questions about links with tuberculosis and refractory anemia.
一名82岁女性，因发热和乏力就诊，发现有颈部淋巴结病。临床和影像学检查均无结果。实验室检查发现难治性贫血。切除淋巴结，触片显示有大量滴虫。组织学上，淋巴结呈现干酪样坏死和巨噬细胞反应。诊断为口腔毛滴虫引起的淋巴结感染。三周后，淋巴结培养显示结核分枝杆菌，由此我们推断存在合并感染。口腔毛滴虫通常被认为是口腔无害腐生菌。这一特殊观察首次显示了口腔毛滴虫的侵袭潜力。它引发了关于与结核病和难治性贫血之间联系的问题。
