Magee D F, Hu C Y
Ann Surg. 1975 Aug;182(2):121-3. doi: 10.1097/00000658-197508000-00006.
Heidenhain pouches, in dogs with simple gastric fistulae, were distended with saline (30, 60 and 90 ml). Pouch acid and pepsin increased linearly with increasing saline volume. Additional pentagastrin augmented the acid but antagonized the pepsin responses. Atropine depressed both the acid and pepsin responses to distention. Ganglionic blockade and local anesthetization of the secretory mucosa also depressed the acid but spared the pepsin response.
在患有单纯胃瘘的狗身上,海登海因袋用生理盐水(30、60和90毫升)扩张。袋内的胃酸和胃蛋白酶随着生理盐水体积的增加呈线性增加。额外的五肽胃泌素增加了胃酸,但拮抗了胃蛋白酶的反应。阿托品抑制了胃酸和胃蛋白酶对扩张的反应。神经节阻断和分泌性黏膜的局部麻醉也抑制了胃酸,但保留了胃蛋白酶的反应。