虹膜炎患者血清中巨噬细胞移动抑制因子增加。
Increase of macrophage migration inhibitory factor in sera of patients with iridocyclitis.
作者信息
Kitaichi N, Kotake S, Mizue Y, Matsuda H, Onoé K, Nishihira J
机构信息
Department of Ophthalmology, Hokkaido University Graduate School of Medicine, Japan.
出版信息
Br J Ophthalmol. 2000 Dec;84(12):1423-5. doi: 10.1136/bjo.84.12.1423.
Abstract
AIMS
To determine whether macrophage migration inhibitory factor (MIF) levels were increased in sera of the patients with iridocyclitis.
METHODS
Sera were obtained from 41 patients with acute iridocyclitis, 13 patients with chronic iridocyclitis, and 44 healthy control subjects. MIF levels were determined by a human MIF ELISA.
RESULTS
The average levels of MIF in the sera of patients with both acute and chronic iridocyclitis were significantly higher than that of healthy subjects.
CONCLUSION
Uveitis induces the elevation of serum MIF, which may affect various inflammatory symptoms in uveitis.
摘要
目的
确定虹膜睫状体炎患者血清中巨噬细胞移动抑制因子（MIF）水平是否升高。
方法
采集41例急性虹膜睫状体炎患者、13例慢性虹膜睫状体炎患者和44例健康对照者的血清。采用人MIF酶联免疫吸附测定法测定MIF水平。
结果
急性和慢性虹膜睫状体炎患者血清中MIF的平均水平均显著高于健康受试者。
结论
葡萄膜炎可导致血清MIF升高，这可能影响葡萄膜炎的各种炎症症状。
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