Schaumann R, Ackermann G, Pless B, Claros M C, Goldstein E J, Rodloff A C
Institute for Medical Microbiology and Epidemiology of Infectious Diseases, University of Leipzig, Liebigstr. 24, D-04103, Leipzig, Germany.
Int J Antimicrob Agents. 2000 Nov;16(3):225-32. doi: 10.1016/s0924-8579(00)00186-2.
The in vitro activities of fourteen antimicrobial agents were tested against 292 clinical isolates of obligately anaerobic bacteria using the broth microdilution technique. Taking all strains as a group the MIC(50/90) (mg/l) values were metronidazole and imipenem 0.25/1, meropenem 0.25/0.5, trovafloxacin 0.25/1, gatifloxacin and moxifloxacin 0.5/2, levofloxacin 2/16, ciprofloxacin 4/32, clindamycin 0.5/8, amoxycillin/clavulanate 1/4, doxycycline and chloramphenicol 2/4, erythromycin 4/>32 and penicillin G 16/>32.
采用肉汤微量稀释技术，对14种抗菌药物针对292株专性厌氧菌临床分离株的体外活性进行了测试。将所有菌株作为一组，甲硝唑和亚胺培南的MIC（50/90）（mg/l）值分别为0.25/1，美罗培南为0.25/0.5，曲伐沙星为0.25/1，加替沙星和莫西沙星为0.5/2，左氧氟沙星为2/16，环丙沙星为4/32，克林霉素为0.5/8，阿莫西林/克拉维酸为1/4，多西环素和氯霉素为2/4，红霉素为4/>32，青霉素G为16/>32。
