Achiron R, Kreiser D, Achiron A
Department of Obstetrics and Gynecology, The Chaim Sheba Medical Center, Tel Hashomer, Israel.
Prenat Diagn. 2000 Nov;20(11):894-9. doi: 10.1002/1097-0223(200011)20:11<894::aid-pd949>3.0.co;2-j.
The aims of this prospective, cross-sectional study were to report axial ocular growth during human gestation, to determine the presence of the hyaloid artery (HA) and its blood flow, and to provide a timetable for HA regression. The study group comprised 231 low-risk singleton pregnancies between 14 and 38 weeks' gestation. Ocular axial length (OAL), anterior chamber depth (ACD) and posterior chamber depth (PCD) were measured using high-resolution ultrasound. The growth of these eye segments in correlation with gestational age (GA) was established. The presence of the HA and its regression were determined. By using power Doppler, ultrasound blood flow within the HA was estimated. HA regression is a gradual process that is not evident before 18 weeks' gestation. In all fetuses beyond 29 weeks' gestation, no HA could be detected (P<0.001). Blood flow within the HA was documented only until the 16th week of gestation. The correlation coefficients, r=0.924, 0.784 and 0.929, for OAL, ACD and PCD, respectively, were found to be highly statistically significant (P<0.0001). The present data offer normative measurements of the fetal axial eye lengths, timetable for HA regression and flow cessation.
这项前瞻性横断面研究的目的是报告人类妊娠期眼轴的生长情况，确定玻璃体动脉（HA）的存在及其血流情况，并提供玻璃体动脉消退的时间表。研究组包括231例妊娠14至38周的低风险单胎妊娠。使用高分辨率超声测量眼轴长度（OAL）、前房深度（ACD）和后房深度（PCD）。确定了这些眼段的生长与孕周（GA）的相关性。确定了玻璃体动脉的存在及其消退情况。通过功率多普勒估计玻璃体动脉内的超声血流。玻璃体动脉消退是一个渐进的过程，在妊娠18周前不明显。在所有妊娠29周以上的胎儿中，均未检测到玻璃体动脉（P<0.001）。玻璃体动脉内的血流仅在妊娠第16周前有记录。OAL、ACD和PCD的相关系数分别为r=0.924、0.784和0.929，具有高度统计学意义（P<0.0001）。目前的数据提供了胎儿眼轴长度的规范测量值、玻璃体动脉消退的时间表和血流停止情况。
