来自绿藻石莼的生物活性类固醇。

Biologically active steroid from the green alga Ulva lactuca.

作者信息

Awad N E

机构信息

Pharmacognosy and Chemistry of Medicinal Plants Department, National Research Center, Dokki, Cairo, Egypt.

出版信息

Phytother Res. 2000 Dec;14(8):641-3. doi: 10.1002/1099-1573(200012)14:8<641::aid-ptr668>3.0.co;2-r.

DOI:10.1002/1099-1573(200012)14:8<641::aid-ptr668>3.0.co;2-r

PMID:11114004

Abstract

The marine green alga, Ulva lactuca, was shown to contain 3-O-beta-D glucopyranosyl-stigmasta-5,25-dien. The structure of the compound was established on the basis of its spectroscopic data and it was extracted for the first time from this alga. The topical antiinflammatory activity of this compound was examined using the mouse ear oedema assay as an experimental model of topical inflammation. Also, the antimicrobial activity of the isolated compound was tested against 10 various microorganisms (G+, G-, fungi and yeast strains).

摘要

海洋绿藻石莼被证明含有3 - O - β - D - 吡喃葡萄糖基 - 豆甾 - 5,25 - 二烯。该化合物的结构基于其光谱数据得以确定，并且首次从这种藻类中提取出来。使用小鼠耳肿胀试验作为局部炎症的实验模型，检测了该化合物的局部抗炎活性。此外，还针对10种不同的微生物（革兰氏阳性菌、革兰氏阴性菌、真菌和酵母菌株）测试了分离出的化合物的抗菌活性。