Sanderfoot A A, Assaad F F, Raikhel N V
Department of Energy Plant Research Laboratory, Michigan State University, East Lansing, Michigan 48824, USA.
Plant Physiol. 2000 Dec;124(4):1558-69. doi: 10.1104/pp.124.4.1558.
Many factors have been characterized as essential for vesicle trafficking, including a number of proteins commonly referred to as soluble N-ethylmaleimide-sensitive factor adaptor protein receptor (SNARE) components. The Arabidopsis genome contains a remarkable number of SNAREs. In general, the vesicle fusion machinery appears highly conserved. However, whereas some classes of yeast and mammalian genes appear to be lacking in Arabidopsis, this small plant genome has gene families not found in other eukaryotes. Very little is known about the precise function of plant SNAREs. By contrast, the intracellular localization of and interactions between a large number of plant SNAREs have been determined, and these data are discussed in light of the phylogenetic analysis.
许多因素已被确定为囊泡运输所必需的，包括一些通常被称为可溶性N - 乙基马来酰亚胺敏感因子附着蛋白受体（SNARE）成分的蛋白质。拟南芥基因组包含数量众多的SNARE蛋白。总体而言，囊泡融合机制似乎高度保守。然而，虽然某些类别的酵母和哺乳动物基因在拟南芥中似乎缺失，但这个小的植物基因组拥有其他真核生物中未发现的基因家族。关于植物SNARE蛋白的确切功能知之甚少。相比之下，大量植物SNARE蛋白的细胞内定位及其相互作用已经确定，并根据系统发育分析对这些数据进行了讨论。
