Soule S, Guntner C, Vazquez A, Argandona V, Moyna P, Ferreira F
Departamento de Quimica, Facultad de Ciencias, Montevideo, Uruguay.
Phytochemistry. 2000 Oct;55(3):217-22.
A spirostanic saponin was isolated from the ethanolic extract of the aerial parts of Solanum laxum Steud. The compound, named luciamin, was characterised by NMR spectroscopy, mass spectrometry and chemical methods, as (22R, 25S)-spirost-5-en-3 beta, 15 alpha-diol 3-O-|beta-D-glucopyranosyl (1 --> 2)-beta-D-glucopyranosyl-( 1 --> 4)-[alpha-L-rhamnopyranosyl-( 1 --> 2)]-beta-D-galactopyranoside|. The compound was tested against the aphid Schizaphis graminum by incorporation in artificial diets. It showed a deterrent (toxic) activity against the insect and is the first spirostane glycoside reported to have this activity.
从疏花茄地上部分的乙醇提取物中分离出一种螺甾烷型皂苷。该化合物名为路西明，通过核磁共振光谱、质谱和化学方法鉴定为(22R, 25S)-螺甾-5-烯-3β, 15α-二醇3-O-β-D-吡喃葡萄糖基(1→2)-β-D-吡喃葡萄糖基-(1→4)-[α-L-鼠李吡喃糖基-(1→2)]-β-D-吡喃半乳糖苷。将该化合物掺入人工饲料中对麦二叉蚜进行测试。它对这种昆虫表现出驱避（毒性）活性，是首个被报道具有这种活性的螺甾烷糖苷。
