Casson R, James B, Rubinstein A, Ali H
Br J Ophthalmol. 2001 Mar;85(3):360-2. doi: 10.1136/bjo.85.3.360.
To determine the number of missed points on frequency doubling technology (FDT) perimetry that optimise the sensitivity and specificity of the test and to determine the topographical accuracy of the test in a clinical setting.
In a prospective study, the perimetric data from 99 patients who underwent both FDT perimetry in the screening mode and Humphrey 24-2 (H24-2) were used to determine the sensitivity and specificity of the FDT perimetry compared with the full threshold H24-2 as the gold standard.
Missed points on the FDT perimetry correlated with both the mean deviation and the corrected pattern standard deviation on the Humphrey perimetry. A score assigned to abnormal points on the FDT perimetry and the Humphrey total deviation plot showed a significant correlation for both the location and the depth of the defect. In comparing the Humphrey hemifield test with the FDT perimetry results, if at least one missed point on the frequency doubling test was considered as abnormal then the overall sensitivity of the test was 78.1% and the specificity was 89.1%.
FDT perimetry in the screening mode performed in a clinical setting was highly specific, exhibited reasonable sensitivity, and accurately determined the location and depth of scotomas when compared with the full threshold Humphrey 24-2.
确定频率加倍技术（FDT）视野检查中能优化检测灵敏度和特异性的漏诊点数，并在临床环境中确定该检测的地形学准确性。
在一项前瞻性研究中，采用99例患者的视野检查数据，这些患者均接受了筛查模式下的FDT视野检查和Humphrey 24-2（H24-2）视野检查，以全阈值H24-2作为金标准来确定FDT视野检查的灵敏度和特异性。
FDT视野检查中的漏诊点与Humphrey视野检查中的平均偏差和校正模式标准差均相关。FDT视野检查中异常点的评分与Humphrey总偏差图上的缺陷位置和深度均显示出显著相关性。在比较Humphrey半视野检查与FDT视野检查结果时，如果将频率加倍试验中至少一个漏诊点视为异常，则该检测的总体灵敏度为78.1%，特异性为89.1%。
在临床环境中进行的筛查模式下的FDT视野检查具有高度特异性，表现出合理的灵敏度，与全阈值Humphrey 24-2相比，能准确确定暗点的位置和深度。
