仅使用频率加倍技术视野计进行视野测试的青光眼群体筛查的效果。

Performance of glaucoma mass screening with only a visual field test using frequency-doubling technology perimetry.

作者信息

Tatemichi Masayuki, Nakano Tadashi, Tanaka Katsutoshi, Hayashi Takeshi, Nawa Takeshi, Miyamoto Toshiaki, Hiro Hisanori, Iwasaki Akio, Sugita Minoru

机构信息

Department of Work Systems and Health, Institute of Industrial and Ecological Science, University of Occupational and Environmental Health, Fukuoka, Japan.

出版信息

Am J Ophthalmol. 2002 Oct;134(4):529-37. doi: 10.1016/s0002-9394(02)01684-7.

DOI:10.1016/s0002-9394(02)01684-7

PMID:12383809

Abstract

PURPOSE

To report the performance of glaucoma mass screening with only a visual field test utilizing frequency- doubling technology (FDT) perimetry in general populations.

DESIGN

Hospital and population-based cross-sectional study.

METHODS

This study took place in a multicenter setting. One hundred three consecutive glaucomatous patients and 14,814 persons were randomly selected. We had created a glaucoma screening protocol (GSP) using FDT perimetry (FDT-GSP). Frequency-doubling technology-glaucoma screening protocol was tested on consecutive glaucoma patients diagnosed with Humphrey visual field analyzer (30-2 SITA standard), and then FDT-GSP was applied to general populations. Frequency-doubling technology-glaucoma screening protocol positive subjects were ophthalmologically diagnosed. Detection ability of FDT-GSP was determined in consecutive patients, and the positive predictive value (PPV) of FDT-GSP to detect definitive glaucoma was estimated in general populations.

RESULTS

Frequency-doubling technique-glaucoma screening protocol detected 83.3% and 100% of definitive glaucoma patients with an early (mean deviation [MD] > -6 dB) and more advanced stage (MD < or = -6 dB), respectively. In the population-based screening, there were 660 (4.5%) subjects who had positive FDT-GSP, including 512 in whom no visual field abnormalities (VFA) had been pointed out previously. Of them, 370 subjects underwent ophthalmologic diagnosis. Then, 266 (71.9%, 266/370) subjects had a glaucomatous disk and 167 had definitive glaucomatous VFA. Fifty-five (14.9%) and 39 (10.5%) subjects were diagnosed as having other diseases and as normal, respectively. The PPV of FDT-GSP ranged from 32.6% (167/512)-45.1% (167/370).

CONCLUSIONS

Frequency-doubling technology-based screening with only a visual field test showed reasonable performance on mass screening for detection of definitive glaucoma in this study population, considering the glaucoma prevalence.

摘要

目的

报告仅使用频率加倍技术（FDT）视野检查法在普通人群中进行青光眼群体筛查的效果。

设计

基于医院和人群的横断面研究。

方法

本研究在多中心环境中开展。连续选取了103例青光眼患者和14814人。我们使用FDT视野检查法制定了一项青光眼筛查方案（GSP）（FDT - GSP）。频率加倍技术 - 青光眼筛查方案首先在连续确诊为Humphrey视野分析仪（30 - 2 SITA标准）的青光眼患者中进行测试，然后应用于普通人群。对频率加倍技术 - 青光眼筛查方案呈阳性的受试者进行眼科诊断。在连续患者中确定FDT - GSP的检测能力，并在普通人群中估计FDT - GSP检测确诊青光眼的阳性预测值（PPV）。

结果

频率加倍技术 - 青光眼筛查方案分别检测出83.3%的早期（平均偏差[MD] > -6 dB）和100%的更晚期（MD≤ -6 dB）确诊青光眼患者。在基于人群的筛查中，有660例（4.5%）受试者FDT - GSP呈阳性，其中包括512例之前未指出有视野异常（VFA）的受试者。其中，370例受试者接受了眼科诊断。然后，266例（71.9%，266/370）受试者有青光眼性视盘，167例有确诊的青光眼性VFA。55例（14.9%）和39例（10.5%）受试者分别被诊断为患有其他疾病和正常。FDT - GSP的PPV范围为32.6%（167/512） - 45.1%（167/370）。