Sun J, Misumi J, Shimaoka A, Aoki K, Esaki F
Department of Public Health and Hygiene, Faculty of Medicine, Oita Medical University, Japan.
Eur J Cancer Prev. 2001 Feb;10(1):61-7. doi: 10.1097/00008469-200102000-00007.
In Japan stomach cancer remains the leading cause of cancer-related mortality. We analysed the annual mortality rate of stomach cancer in relation to age, gender and life expectancy in Japan between 1970 and 1995. The adjusted stomach cancer-related mortality rates decreased from 88.9 in 1970 to 45.4 per 100,000 in 1995 in males and from 46.5 to 18.5 per 100,000 in females. The male-female ratio for stomach cancer-related mortality in all ages was 1.9-2.5 during this 25-year period, and the mortality rate was higher in females than in males at young age. The negative contribution to life expectancy for stomach cancer in males was 0.65 years and 0.42 years in females, which is consistent with a higher mortality rate in males. This negative contribution was 41.8% of total cancer in 1970 and 39.4% in 1995 in males and 34.4% and 16.0%, respectively, in females. Our results demonstrated the need to take into consideration the characteristics of stomach cancer in young women and the effects of ageing when designing programmes aimed at prevention and control of this malignancy.
在日本，胃癌仍是癌症相关死亡的主要原因。我们分析了1970年至1995年间日本胃癌的年度死亡率与年龄、性别和预期寿命的关系。男性中，经调整的胃癌相关死亡率从1970年的每10万人88.9例降至1995年的每10万人45.4例；女性中则从每10万人46.5例降至18.5例。在这25年期间，所有年龄段胃癌相关死亡率的男女比例为1.9至2.5，且在年轻时女性的死亡率高于男性。胃癌对男性预期寿命的负贡献为0.65年，对女性为0.42年，这与男性较高的死亡率一致。这种负贡献在1970年占男性总癌症的41.8%，在1995年占39.4%；在女性中分别为34.4%和16.0%。我们的结果表明，在设计针对这种恶性肿瘤的预防和控制方案时，需要考虑年轻女性胃癌的特征以及老龄化的影响。
