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年轻季节性变应性鼻炎患者的健康相关生活质量评估

Health-related quality of life assessment in young adults with seasonal allergic rhinitis.

作者信息

Majani G, Baiardini I, Giardini A, Senna G E, Minale P, D'Ulisse S, Ciprandi G, Canonica G W

机构信息

Servizio di Psicologia, Fondazione S Maugeri, Clinica del Lavoro e della Riabilitazione, IRCCS, Istituto Scientifico di Montescano, Italy.

出版信息

Allergy. 2001 Apr;56(4):313-7. doi: 10.1034/j.1398-9995.2001.00852.x.

Abstract

BACKGROUND

In health-related quality of life (HRQL) studies on allergic rhinitis, both disease-specific and generic questionnaires have been extensively used. Seasonal allergic rhinitis (SAR) has been studied mainly by focusing on symptomatology. The present study aimed to evaluate the SAR-HRQL by means of two questionnaires, the Medical Outcome Study Short Form Health Survey (SF-36) and a new instrument examining satisfaction in 32 aspects of daily life: the Satisfaction Profile (SAT-P).

METHODS

Thirty-three patients with SAR (aged 33.5+/-8.5 years; 12 men, 21 women) were evaluated during and 2 months after the pollen season. Data were compared with reference samples by t-test, and baseline and follow-up HRQL scores were compared by a matched-pair test.

RESULTS

Patients' HRQL scores collected during the pollen season were significantly lower than reference sample data in many SF-36 scores and in one SAT-P item. No differences emerged between SF-36 and SAT-P scores collected outside the pollen season and reference sample scores. Compared to baseline, outside the pollen season, patients reported significantly higher scores in the following SF-36 scales: physical functioning (P=0.002), physical role (P=0.00001), bodily pain (P=0.01), and vitality (P=0.008); and significantly higher scores in only two SAT-P items (physical well-being [P=0.009] and resistance to stress [P=0.01]).

CONCLUSIONS

Our data confirm the utility of using symptomatologic and health-status questionnaires in evaluating the HRQL of SAR patients. More general quality of life questionnaires may prevent the symptomatologic and functional problems from being adequately recognized and managed. SAT-P can be a fruitful additional tool in HRQL evaluation.

摘要

背景

在变应性鼻炎的健康相关生活质量(HRQL)研究中,疾病特异性问卷和通用问卷均被广泛使用。季节性变应性鼻炎(SAR)主要通过关注症状学进行研究。本研究旨在通过两份问卷评估SAR-HRQL,这两份问卷分别是医学结局研究简表健康调查(SF-36)和一份新的考察日常生活32个方面满意度的工具:满意度概况(SAT-P)。

方法

在花粉季节期间及之后2个月对33例SAR患者(年龄33.5±8.5岁;男性12例,女性21例)进行评估。通过t检验将数据与参考样本进行比较,并通过配对检验比较基线和随访时的HRQL评分。

结果

在花粉季节期间收集的患者HRQL评分在许多SF-36评分以及一个SAT-P项目中显著低于参考样本数据。在花粉季节之外收集的SF-36和SAT-P评分与参考样本评分之间未发现差异。与基线相比,在花粉季节之外,患者在以下SF-36量表中报告的评分显著更高:生理功能(P=0.0??)、生理角色(P=0.00001)、身体疼痛(P=0.01)和活力(P=0.008);并且仅在两个SAT-P项目(身体健康[P=0.009]和抗压能力[P=0.01])中评分显著更高。

结论

我们的数据证实了使用症状学和健康状况问卷评估SAR患者HRQL的实用性。更通用的生活质量问卷可能会妨碍对症状学和功能问题的充分认识及处理。SAT-P可以成为HRQL评估中一个有效的补充工具。

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