Zehong W, Lezheng W, De-zheng W, Jiongji L
Zhongshan Ophthalmic Center, Sun Yat-sen University of Medical Sciences, Guangzhou 510060, China.
Yan Ke Xue Bao. 1997 Sep;13(3):128-32.
To objectively evaluate the clinical application of color pattern reversal visual evoked potential (CPR-VEP) on primary open angle glaucoma (POAG).
CPR-VEP and FM 100-hue test were performed in 31 eyes with POAG and 33 normal eyes. Color pattern stimulation was presented by color monitor controlled by computer program. The reversal rate of the stimulating pattern was 2 Hz and the spatial frequency of the stimulating was 0.53 cycle/degree. The color stimulating pattern include White/Black, Red/Black, Green/Black, Blue/Black, Yellow/Black, Red/Green and Blue/Yellow.
CPR-VEP P1 latencies were obviously prolonged in POAG group in comparison with normal control group in equiluminance. All CPR-VEP P1 amplitudes, except Blue/Black P1 amplitude, show no differences between POAG group and normal control group.
P1 latencies of all CPR-VEP and P1 amplitude of Blue/Black CPR-VEP were parameters for identifying acquired dyschromatopsia caused by POAG. The results showed nonselective damages in color channels and luminance channel in POAG. CPR-VEP is helpful in detecting acquired dyschromatopsia.
客观评估彩色模式翻转视觉诱发电位（CPR-VEP）在原发性开角型青光眼（POAG）中的临床应用。
对31只POAG患眼和33只正常眼进行CPR-VEP及FM 100色相试验。彩色模式刺激由计算机程序控制的彩色显示器呈现。刺激模式的翻转率为2Hz，刺激的空间频率为0.53周/度。彩色刺激模式包括白/黑、红/黑、绿/黑、蓝/黑、黄/黑、红/绿和蓝/黄。
在等亮度条件下，POAG组的CPR-VEP P1潜伏期较正常对照组明显延长。除蓝/黑P1波幅外，POAG组与正常对照组的所有CPR-VEP P1波幅均无差异。
所有CPR-VEP的P1潜伏期及蓝/黑CPR-VEP的P1波幅是识别POAG所致后天性色觉障碍的参数。结果显示POAG中色觉通道和亮度通道均存在非选择性损害。CPR-VEP有助于检测后天性色觉障碍。
