Avery D H, Kizer D, Bolte M A, Hellekson C
Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Harborview Medical Center, Seattle, WA 98104, USA.
Acta Psychiatr Scand. 2001 Apr;103(4):267-74. doi: 10.1034/j.1600-0447.2001.00078.x.
Bright light therapy in seasonal affective disorder (SAD) has been studied extensively. However, little attention has been given to subsyndromal seasonal affective disorder (SSAD) or the use of bright light in the workplace. Many patients using bright light boxes complain of the inconvenience of use. Much of this inconvenience involves the often-recommended early timing of the bright light therapy. Patients, who already have difficulty awakening, often have difficulty using the bright light therapy soon after awakening before going to work. If bright light could be used effectively in the workplace, the treatment would be more convenient; the improved convenience would probably improve compliance. In this study, we studied the effectiveness of bright light therapy in subjects with SSAD in the workplace, comparing morning bright light with afternoon bright light.
Morning and afternoon bright light treatment (2500 lux) were compared in 30 subsyndromal seasonal affective disorder patients using the bright light therapy in the workplace. Hamilton Depression Ratings and subjective measures of mood, energy, alertness and productivity were assessed before and after 2 weeks of light therapy.
Both morning and evening bright light significantly decreased the depression ratings and improved the subjective mood, energy, alertness and productivity scores. However, there were no significant differences between the two times of administration of the bright light treatment. Both bright light treatments were well tolerated.
Bright light given in the workplace improves subjective ratings of mood, energy, alertness and productivity in SSAD subjects. Morning and afternoon bright lights resulted in similar levels of improvement.
季节性情感障碍（SAD）的强光疗法已得到广泛研究。然而，对于亚综合征性季节性情感障碍（SSAD）或在工作场所使用强光的关注却很少。许多使用强光箱的患者抱怨使用不便。这种不便很大程度上涉及通常建议的强光治疗的早起时间。那些本身就难以醒来的患者，在醒来后上班前很快使用强光疗法往往会有困难。如果能在工作场所有效使用强光，治疗将会更方便；便利性的提高可能会改善依从性。在本研究中，我们研究了在工作场所对SSAD患者进行强光疗法的有效性，比较了早晨强光与下午强光的效果。
在工作场所使用强光疗法的30例亚综合征性季节性情感障碍患者中，比较早晨和下午的强光治疗（2500勒克斯）。在强光治疗2周前后，评估汉密尔顿抑郁量表评分以及情绪、精力、警觉性和工作效率的主观指标。
早晨和晚上的强光均显著降低了抑郁评分，并改善了主观情绪、精力、警觉性和工作效率得分。然而，强光治疗的两个时间点之间没有显著差异。两种强光治疗的耐受性都很好。
在工作场所给予强光可改善SSAD患者的情绪、精力、警觉性和工作效率的主观评分。早晨和下午的强光产生的改善程度相似。
