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Syscan3,一种用于检测抗念珠菌抗体以诊断侵袭性念珠菌病的试剂盒。

Syscan3, a kit for detection of anti-Candida antibodies for diagnosis of invasive candidiasis.

作者信息

Philip Annie, Odabasi Zekaver, Matiuzzi Gloria, Paetznick Victor L, Tan Sze-Wee, Warmington John, Rex John H, Ostrosky-Zeichner Luis

机构信息

Laboratory of Mycology Research, Division of Infectious Diseases, University of Texas-Houston Medical School, 77030, USA.

出版信息

J Clin Microbiol. 2005 Sep;43(9):4834-5. doi: 10.1128/JCM.43.9.4834-4835.2005.

Abstract

Sera from 76 immunocompetent and 293 immunocompromised subjects were assayed for anti-Candida antibodies. The sensitivity, specificity, positive predictive value, and negative predictive value for invasive candidiasis were 74%, 75%, 62%, and 84% in the immunocompetent group and 15%, 60%, 1.7%, and 93% in the immunocompromised group, respectively. Syscan3 has high negative predictive value.

摘要

对76名免疫功能正常和293名免疫功能低下受试者的血清进行了抗念珠菌抗体检测。免疫功能正常组侵袭性念珠菌病的敏感性、特异性、阳性预测值和阴性预测值分别为74%、75%、62%和84%,免疫功能低下组分别为15%、60%、1.7%和93%。Syscan3具有较高的阴性预测值。

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