Wines N, Willsteed E
Department of Dermatology, Royal North Shore Hospital, Sydney, Australia.
Australas J Dermatol. 2001 Aug;42(3):149-8; quiz 159. doi: 10.1046/j.1440-0960.2001.00524.x.
Women live one-third of their lives in the post-menopausal state. Significant hormonal alterations occur at the time of menopause, leading to a range of physiological disorders affecting multiple organ systems in the body. The effects of menopause on the skin have been underresearched. Many skin changes occur at the time of menopause and the cutaneous effects of hormone replacement therapy are significant. Menopausal changes in hormones may alter the biomechanical properties of the skin and certain disorders are more common in menopausal women, such as lichen sclerosus, atrophic vulvovaginitis, flushing and dysaesthetic vulvodynia. Hair and oral changes may also be associated. As the average life expectancy increases, dermatologists need to be familiar with skin diseases affecting women in this age group.
女性一生中有三分之一的时间处于绝经后状态。绝经时会发生显著的激素变化,导致一系列影响身体多个器官系统的生理紊乱。绝经对皮肤的影响研究较少。绝经时会出现许多皮肤变化,激素替代疗法对皮肤的影响也很显著。绝经时激素的变化可能会改变皮肤的生物力学特性,某些疾病在绝经后女性中更为常见,如硬化性苔藓、萎缩性外阴阴道炎、潮热和感觉异常性外阴痛。毛发和口腔变化也可能与之相关。随着平均预期寿命的增加,皮肤科医生需要熟悉影响这个年龄段女性的皮肤疾病。