正常压力脑积水的单胺酸代谢产物与脑脊液动力学：初步结果
Monoamine acid metabolites and cerebrospinal fluid dynamics in normal pressure hydrocephalus: preliminary results.
作者信息
Maira G, Bareggi S R, Di Rocco C, Calderini G, Morselli P L
出版信息
J Neurol Neurosurg Psychiatry. 1975 Feb;38(2):123-8. doi: 10.1136/jnnp.38.2.123.
Abstract
Lumbar and ventricular CSF concentration of homovanillic acid (HVA) and 5-hydroxy-indole-acetic acid (5-HIAA) have been determined in 13 patients admitted to hospital for suspected normal pressure hydrocephalus. Low values of HVA in lumbar CSF were found in all patients with reduced CSF absorption and CSF flow inversion. The HVA lumbar concentration remained low after shunt procedure; it increased if obstruction of the shunt occurred. The ventricular CSF concentration of HVA was normal before surgery; it became higher, in two cases, after surgery. No important variations were found in the lumbar and ventricular CSF concentration of 5-HIAA. The possible mechanisms and diagnostic value of these findings are discussed.
摘要
对13名因疑似正常压力脑积水入院的患者测定了腰椎和脑室脑脊液中高香草酸（HVA）和5-羟吲哚乙酸（5-HIAA）的浓度。在所有脑脊液吸收减少和脑脊液流动逆转的患者中，腰椎脑脊液中的HVA值均较低。分流手术后，腰椎脑脊液中HVA的浓度仍较低；如果分流管发生阻塞，其浓度会升高。术前脑室脑脊液中HVA的浓度正常；术后有两例升高。5-HIAA在腰椎和脑室脑脊液中的浓度未发现明显变化。讨论了这些发现的可能机制和诊断价值。
相似文献
1
Monoamine acid metabolites and cerebrospinal fluid dynamics in normal pressure hydrocephalus: preliminary results.正常压力脑积水的单胺酸代谢产物与脑脊液动力学：初步结果
J Neurol Neurosurg Psychiatry. 1975 Feb;38(2):123-8. doi: 10.1136/jnnp.38.2.123.
2
Homovanillic acid and 5-hydroxyindoleacetic acid in the ventricular CSF of comatose patients with obstructive hydrocephalus.梗阻性脑积水昏迷患者脑室脑脊液中的高香草酸和5-羟吲哚乙酸
J Neurosurg. 1980 May;52(5):635-41. doi: 10.3171/jns.1980.52.5.0635.
3
Sites of origin in the central nervous system of monoamine metabolites measured in human cerebrospinal fluid.在人类脑脊液中测量的单胺代谢产物在中枢神经系统中的起源部位。
J Neurol Neurosurg Psychiatry. 1973 Aug;36(4):625-9. doi: 10.1136/jnnp.36.4.625.
4
Concentrations of monoamine metabolites in human lumbar and cisternal cerebrospinal fluid.人腰椎和脑池脑脊液中单胺代谢物的浓度。
Acta Neurol Scand. 1975 Aug;52(2):137-44. doi: 10.1111/j.1600-0404.1975.tb05767.x.
5
Concentration gradients of monoamine metabolites in human cerebrospinal fluid.人脑脊液中单胺代谢物的浓度梯度
J Neurol Neurosurg Psychiatry. 1975 Jul;38(7):666-8. doi: 10.1136/jnnp.38.7.666.
6
Concentration of homovanillic acid and 5-hydroxyindoleacetic acid in the ventricular cerebrospinal fluid of patients with obstructive hydrocephalus.梗阻性脑积水患者脑室脑脊液中高香草酸和5-羟吲哚乙酸的浓度。
J Neurol Neurosurg Psychiatry. 1979 Jan;42(1):78-81. doi: 10.1136/jnnp.42.1.78.
7
Nonhomogeneous distribution of 5-hydroxyindoleacetic acid and homovanillic acid in the lumbar cerebrospinal fluid of man.人腰椎脑脊液中5-羟吲哚乙酸和高香草酸的非均匀分布。
J Neurol Sci. 1977 Mar;31(2):165-71. doi: 10.1016/0022-510x(77)90103-4.
8
Monoamine acid metabolites in ventricular CSF of patients with brain tumours.脑肿瘤患者脑室脑脊液中的单胺酸代谢产物。
Acta Neurochir (Wien). 1976;35(1-3):161-70. doi: 10.1007/BF01405944.
9
Monoamine metabolites in the CSF of epileptic patients.癫痫患者脑脊液中的单胺代谢产物。
Neurology. 1979 Aug;29(8):1157-61. doi: 10.1212/wnl.29.8.1157.
10
[Physiopathology of neurotransmitter metabolites in the cerebrospinal fluid in brain tumors].[脑肿瘤患者脑脊液中神经递质代谢产物的病理生理学]
Minerva Med. 1984 May 19;75(21):1279-86.
引用本文的文献
1
Do concentrations of neurotransmitters measured in lumbar cerebrospinal fluid reflect the concentrations at brain level?在腰椎脑脊液中测得的神经递质浓度能否反映大脑水平的浓度？
Acta Neurochir (Wien). 1988;91(1-2):55-9. doi: 10.1007/BF01400529.
2
CSF monoamine metabolites, cholinesterases and lactate in the adult hydrocephalus syndrome (normal pressure hydrocephalus) related to CSF hydrodynamic parameters.成人脑积水综合征（正常压力脑积水）中脑脊液单胺代谢产物、胆碱酯酶和乳酸与脑脊液流体动力学参数的关系
J Neurol Neurosurg Psychiatry. 1991 Mar;54(3):252-9. doi: 10.1136/jnnp.54.3.252.
3
Surgical indications in normotensive hydrocephalus. A retrospective analysis of the relations of some diagnostic findings to the results of surgical treatment.正常压力脑积水的手术指征。对一些诊断结果与手术治疗效果之间关系的回顾性分析。
Acta Neurochir (Wien). 1976;33(1-2):1-21. doi: 10.1007/BF01405737.
4
Monoamine acid metabolites in ventricular CSF of patients with brain tumours.脑肿瘤患者脑室脑脊液中的单胺酸代谢产物。
Acta Neurochir (Wien). 1976;35(1-3):161-70. doi: 10.1007/BF01405944.
5
Syndrome of normal pressure hydrocephalus: possible relation to hypertensive and arteriosclerotic vasculopathy.正常压力脑积水综合征：与高血压和动脉硬化性血管病的可能关系。
J Neurol Neurosurg Psychiatry. 1977 Jan;40(1):73-9. doi: 10.1136/jnnp.40.1.73.
6
Accuracy of ventricular volume estimation.心室容积估计的准确性。
J Neurol Neurosurg Psychiatry. 1979 Apr;42(4):345-50. doi: 10.1136/jnnp.42.4.345.
7
Concentration of homovanillic acid and 5-hydroxyindoleacetic acid in the ventricular cerebrospinal fluid of patients with obstructive hydrocephalus.梗阻性脑积水患者脑室脑脊液中高香草酸和5-羟吲哚乙酸的浓度。
J Neurol Neurosurg Psychiatry. 1979 Jan;42(1):78-81. doi: 10.1136/jnnp.42.1.78.
本文引用的文献
1
SYMPTOMATIC OCCULT HYDROCEPHALUS WITH "NORMAL" CEREBROSPINAL-FLUID PRESSURE. A TREATABLE SYNDROME.具有“正常”脑脊液压力的症状性隐匿性脑积水。一种可治疗的综合征。
N Engl J Med. 1965 Jul 15;273:117-26. doi: 10.1056/NEJM196507152730301.
2
Increased level of 5-hydroxyindoleacetic acid in cerebrospinal fluid from infantile hydrocephalus.婴儿脑积水患者脑脊液中5-羟吲哚乙酸水平升高。
Experientia. 1966 Aug 15;22(8):539-40. doi: 10.1007/BF01898679.
3
The special clinical problem of symptomatic hydrocephalus with normal cerebrospinal fluid pressure. Observations on cerebrospinal fluid hydrodynamics.症状性正常脑脊液压力脑积水的特殊临床问题。脑脊液流体动力学观察。
J Neurol Sci. 1965 Jul-Aug;2(4):307-27. doi: 10.1016/0022-510x(65)90016-x.
4
Relationship between cerebrospinal fluid formation, absorption and pressure in human hydrocephalus.人类脑积水时脑脊液生成、吸收与压力之间的关系。
Brain. 1970;93(4):679-92. doi: 10.1093/brain/93.4.679.
5
Cerebrospinal fluid formation and absorption and transport of iodide and sulfate from the spinal subarachnoid space.脑脊液的形成、吸收以及碘化物和硫酸盐从脊髓蛛网膜下腔的转运。
J Neurol Sci. 1970 Mar;10(3):247-58. doi: 10.1016/0022-510x(70)90153-x.
6
5-hydroxyindoleacetic acid in cerebrospinal fluid of hydrocephalic children.脑积水患儿脑脊液中的5-羟吲哚乙酸
Acta Paediatr Scand. 1969 Nov;58(6):601-8. doi: 10.1111/j.1651-2227.1969.tb04768.x.
7
Amine metabolites in the lumbar cerebrospinal fluid of humans with restricted flow of cerebrospinal fluid.脑脊液流动受限的人类腰椎脑脊液中的胺类代谢产物。
Nat New Biol. 1971 Jun 9;231(23):189-91. doi: 10.1038/newbio231189a0.
8
Effect of intravenously administered probenecid in humans on the levels of 5-hydroxyindoleacetic acid, homovanillic acid and 3-methoxy-4-hydroxy-phenylglycol in cerebrospinal fluid.静脉注射丙磺舒对人体脑脊液中5-羟吲哚乙酸、高香草酸和3-甲氧基-4-羟基苯乙二醇水平的影响。
Biochem Pharmacol. 1971 Mar;20(3):659-68. doi: 10.1016/0006-2952(71)90152-3.
9
Origin of 5-hydroxyindoleacetic acid in the spinl fluid.脊髓液中5-羟吲哚乙酸的来源。
Science. 1971 Aug 20;173(3998):738-40. doi: 10.1126/science.173.3998.738.
10
Experimental hydrocephalus. Changes in cerebrospinal fluid dynamics as a function of time.实验性脑积水。脑脊液动力学随时间的变化。
Arch Neurol. 1972 Feb;26(2):120-9. doi: 10.1001/archneur.1972.00490080038003.
Zotero 插件