Paspatis G A, Papanikolaou N, Zois E, Michalodimitrakis E
Department of Gastroenterology, Benizelion General Hospital, Heraklion-Crete, Greece.
Int J Colorectal Dis. 2001 Aug;16(4):257-61. doi: 10.1007/s003840100304.
While a number of studies have been performed in the United States, northern Europe, and some other countries on the epidemiology of large bowel polyps and diverticulosis, information from southern Europe and especially Greece is very limited. Our autopsy study sought to determine the prevalence of large bowel polyps and diverticulosis in the population on Crete. Specimens of colon and rectum were obtained during forensic postmortem autopsies and examined for the presence of polypoid lesions and diverticulosis. Data were collected from a total of 502 autopsies (320 men, 182 women; median age 65 years (range 16-93). Polyps were found in 106 cases (21.1%). These were adenomas in 73 cases (14.5%), hyperplastic polyps in 25 (4.9%), and mucosal tags in 8 (1.5%). Diverticulosis of the large bowel was found in 115 (22.9%). The prevalence of adenomas and diverticulosis increased with advanced age. The prevalence of colonic diverticulosis in Crete is slightly lower than that which has been reported in most other studies in economically developed countries. The prevalence of colorectal adenomas in Crete is one of the lowest rates reported in Europe and is compatible to the known low incidence of colorectal cancer in Crete.
虽然在美国、北欧和其他一些国家已经开展了多项关于大肠息肉和憩室病流行病学的研究，但来自南欧尤其是希腊的信息非常有限。我们的尸检研究旨在确定克里特岛人群中大肠息肉和憩室病的患病率。在法医尸检过程中获取结肠和直肠标本，检查是否存在息肉样病变和憩室病。总共收集了502例尸检的数据（320名男性，182名女性；中位年龄65岁（范围16 - 93岁））。106例（21.1%）发现息肉。其中腺瘤73例（14.5%），增生性息肉25例（4.9%），黏膜赘生物8例（1.5%）。大肠憩室病在115例（22.9%）中被发现。腺瘤和憩室病的患病率随年龄增长而增加。克里特岛结肠憩室病的患病率略低于经济发达国家大多数其他研究报告的患病率。克里特岛结直肠腺瘤的患病率是欧洲报告的最低患病率之一，与克里特岛已知的低结直肠癌发病率相符。
