Williams A R, Balasooriya B A, Day D W
Gut. 1982 Oct;23(10):835-42. doi: 10.1136/gut.23.10.835.
In a prospective necropsy study of the large bowel in 365 cases, the commonest polyp identified was the hyperplastic (metaplastic) variety, of which 86.1% of the total were located in the rectum. The other main type of polyp found, and of much greater importance because of its malignant potential, was the neoplastic adenoma. These were present, either singly or multiply, in 73 of 198 male cases (36.9%) and in 48 of 167 female cases (28.7%). Their prevalence and their tendency to be multiple rose with increasing age in both sexes. Most adenomas had a tubular growth pattern and 88.8% of these were under 1 cm in diameter. There was a fairly even distribution of adenomas throughout the large bowel but a higher proportion of adenomas over 1 cm in diameter occurred in the caecum, sigmoid colon, and rectum than at other sites. In the whole series nine adenocarcinomas were present, two of which were arising in adenomas.
在一项对365例大肠进行的前瞻性尸检研究中，最常见的息肉类型是增生性（化生型）息肉，其中86.1%位于直肠。发现的另一种主要息肉类型，因其具有恶变潜能而更为重要，是肿瘤性腺瘤。在198例男性病例中有73例（36.9%）存在单发或多发的腺瘤，在167例女性病例中有48例（28.7%）存在。两性中腺瘤的患病率及其多发倾向均随年龄增长而上升。大多数腺瘤呈管状生长模式，其中88.8%直径小于1厘米。腺瘤在整个大肠中分布较为均匀，但直径超过1厘米的腺瘤在盲肠、乙状结肠和直肠中的比例高于其他部位。在整个系列中共有9例腺癌，其中2例起源于腺瘤。
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