Stark C E, Squire L R
Department of Psychiatry, University of California San Diego, 92093, USA.
Learn Mem. 2001 Jul-Aug;8(4):190-7. doi: 10.1101/lm.40701.
Although it is well established that the hippocampal region is involved in the formation of declarative memory, the exact nature of its involvement is unclear. One view is that the hippocampal region is involved only in tasks that require the formation or use of associations. According to this view, the hippocampal region is not involved in traditional tests of recognition memory. An alternative view is that the hippocampal region combines and extends the processing carried out by structures in the parahippocampal gyrus and that it is involved in all forms of declarative memory, including recognition memory. Using event-related functional magnetic resonance imaging (fMRI), we observed hippocampal activity during both traditional and associative recognition memory tasks. Critically, the hippocampal region was no more active in the associative recognition task than in the traditional recognition task.
虽然海马体区域参与陈述性记忆的形成这一点已得到充分证实，但其具体参与方式尚不清楚。一种观点认为，海马体区域仅参与需要形成或运用关联的任务。按照这种观点，海马体区域不参与传统的识别记忆测试。另一种观点则认为，海马体区域整合并扩展了海马旁回结构所进行的加工，并且它参与所有形式的陈述性记忆，包括识别记忆。通过事件相关功能磁共振成像（fMRI），我们在传统和关联性识别记忆任务中均观察到了海马体的活动。关键在于，海马体区域在关联性识别任务中的活跃度并不高于传统识别任务。
