Götestam K G, Lewander T
Psychopharmacologia. 1975 Apr 30;42(1):41-5. doi: 10.1007/BF00428823.
Rats were given dl-amphetamine 16 mg/kg twice daily for 15 days. Complete tolerance to the anorexigenic effect of amphetamine developed from day 7--11. A single injection of 16 mg/kg amphetamine was given to the amphetamine pretreated rats and to saline pretreated controls at different time-points after withdrawal, and their food intakes were compared. Signs of tolerance were present in 16 but not 20 days after withdrawal.
给大鼠每日两次注射16毫克/千克的dl-苯丙胺，持续15天。从第7天至第11天，大鼠对苯丙胺的厌食作用产生了完全耐受性。在撤药后的不同时间点，给预先接受苯丙胺处理的大鼠和接受生理盐水处理的对照大鼠单次注射16毫克/千克的苯丙胺，并比较它们的食物摄入量。撤药后16天出现耐受性迹象，而20天时未出现。
