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Impairment of human sperm motility and viability by quercetin is independent of lipid peroxidation.

作者信息

Khanduja K L, Verma A, Bhardwaj A

机构信息

Department of Biophysics, Postgraduate Institute of Medical Education & Research, Chandigarh 160012, India.

出版信息

Andrologia. 2001 Sep;33(5):277-81. doi: 10.1046/j.1439-0272.2001.00432.x.

DOI:10.1046/j.1439-0272.2001.00432.x
PMID:11683702
Abstract

Human sperm motility, viability and lipid peroxidation were assessed in Ringer-Tyrode supplemented with different concentrations of quercetin. An irreversible and dose-dependent fall in sperm motility was observed with quercetin (5-200 microm). However, sperm viability was decreased only at higher concentrations (50-100 microm) of quercetin. This inhibition in sperm motility and viability has been linked with decreased Ca2+-ATPase activity, as there was no effect of quercetin on sperm lipid peroxidation.

摘要

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