Beylot C
Service de dermatologie Hôpital du Haut-Lévêque CHU de Bordeaux 33604 Pessac.
Rev Prat. 1998 May 1;48(9):951-6.
Atopic dermatitis is an extremely common condition whose prevalence is on the increasing for the past three decades particularly in North Europe, where it affects 15% of children, since birth to seventh year. A simultaneous increase of atopic respiratory disorders such as asthma and allergic rhinitis has been reported. Clinical diagnostic criteria of atopic dermatitis are well known and the recent studies concern particularly the interactions between genetic and environmental provocative factors, such as house dust mites, maternal smoking and food allergens. In susceptible families, the maternal and infants avoidance of these triggers may allow to decrease the incidence or the severity of atopic dermatitis. The conventional treatment remains symptomatic with topical steroids. However, the better understanding of pathogenesis of atopic dermatitis holds the hope of immunomodulating treatment, particularly in refractory cases.
特应性皮炎是一种极为常见的病症，在过去三十年中其患病率呈上升趋势，尤其是在北欧，从出生到七岁的儿童中有15%受其影响。据报道，哮喘和过敏性鼻炎等特应性呼吸道疾病也同时增加。特应性皮炎的临床诊断标准广为人知，最近的研究尤其关注遗传因素与环境诱发因素之间的相互作用，如屋尘螨、母亲吸烟和食物过敏原。在易感家庭中，母亲和婴儿避免接触这些诱因可能会降低特应性皮炎的发病率或严重程度。传统治疗仍然是使用局部类固醇进行对症治疗。然而，对特应性皮炎发病机制的深入了解为免疫调节治疗带来了希望，尤其是在难治性病例中。
