Nguyen L T, Janssen C R
Laboratory of Environmental Toxicology and Aquatic Ecology, Ghent University J. Plateaustraat 22, 9000 Ghent, Belgium.
Environ Toxicol. 2001;16(6):566-71.
Embryo-larval toxicity tests with the African catfish (Clarias gariepinus) were conducted with five chemicals (Cr, Cd, Zn, NaPCP and malathion) and three environmental samples. The sensitivity of the 5-day assay was compared to that of the 12-day embryo-larval toxicity tests with the zebra fish (Danio rerio). The ratios of the C. gariepinus and D. rerio LC50 values ranged from 0.4 for Cr to 8.9 for Zn. The ratios of subchronic values ranged from 0.25 for NaPCP to 3.1 for Cd indicating a more comparable sensitivity of the two species. For the three sediment pore waters, the ratios were 0.6, 1.1, and 2.4 and the subchronic values were identical for the two species. The results suggest that, considering the short-test duration and its sensitivity, the 5-day embryo-larval tests with C. gariepinus may be a potential alternative for short-term embryo-larval toxicity testing with fish.
使用非洲鲶鱼（Clarias gariepinus）对五种化学物质（铬、镉、锌、五氯酚钠和马拉硫磷）以及三个环境样本进行了胚胎-幼体毒性试验。将为期5天的试验灵敏度与使用斑马鱼（Danio rerio）进行的为期12天的胚胎-幼体毒性试验的灵敏度进行了比较。非洲鲶鱼和斑马鱼的半数致死浓度（LC50）值之比范围为：铬为0.4，锌为8.9。亚慢性值之比范围为：五氯酚钠为0.25，镉为3.1，这表明这两个物种的灵敏度更具可比性。对于三种沉积物孔隙水，该比值分别为0.6、1.1和2.4，且两个物种的亚慢性值相同。结果表明，考虑到试验持续时间短及其灵敏度，使用非洲鲶鱼进行的为期5天的胚胎-幼体试验可能是鱼类短期胚胎-幼体毒性试验的一个潜在替代方法。
