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系统性红斑狼疮中抗体依赖性细胞介导的细胞毒性降低。

Reduced antibody-dependent cell-mediated cytotoxicity in systemic lupus erythematosus.

作者信息

Schneider J, Chin W, Friou G J, Cooper S M, Harding B, Hill R L, Quismorio F P

出版信息

Clin Exp Immunol. 1975 May;20(2):187-92.

Abstract

The peripheral blood mononuclear cells from twenty-three patients with SLE were studied. They showed a reduction in antibody-dependent cell-mediated cytotoxicity. This reduction was significantly related to disease activity. No correlations were found with other clinical features. Some of the possible explanations for this finding are discussed.

摘要

对23例系统性红斑狼疮患者的外周血单个核细胞进行了研究。这些细胞显示出抗体依赖性细胞介导的细胞毒性降低。这种降低与疾病活动度显著相关。未发现与其他临床特征存在相关性。文中讨论了这一发现的一些可能解释。

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