正常人和类风湿患者中参与抗体介导细胞毒性的细胞毒性淋巴细胞的功能测定。
Functional assay of cytotoxic lymphocytes involved in antibody-mediated cytotoxicity in normal and rheumatoid subjects.
作者信息
Panayi G S, Corrigall V
出版信息
Ann Rheum Dis. 1977 Jun;36(3):257-60. doi: 10.1136/ard.36.3.257.
Abstract
Antibody-mediated lymphocyte-induced cytotoxicity (K cell activity) was measured in a system consisting of Chang human liver cells, rabbit anti-Chang antiserum, and Triosil-Ficoll purified human lymphocytes. It was concluded that one K cell probably inactivates or kills one target cell, and that the number of active K cells is similar in the peripheral blood of normal and rheumatoid subjects and is about 0-5%.
摘要
在一个由张氏人肝细胞、兔抗张氏抗血清和三硅醇-聚蔗糖纯化的人淋巴细胞组成的系统中，检测了抗体介导的淋巴细胞诱导的细胞毒性（K细胞活性）。得出的结论是，一个K细胞可能使一个靶细胞失活或杀死一个靶细胞，并且正常人和类风湿患者外周血中活性K细胞的数量相似，约为0 - 5%。
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