Nam Hyeran, Ha Misun, Bae On, Lee Yeonhee
Department of Biotechnology, Seoul Women's University, Seoul 139-774, Korea.
Appl Environ Microbiol. 2002 Sep;68(9):4642-5. doi: 10.1128/AEM.68.9.4642-4645.2002.
Viable and nonviable Weissella confusa strain PL9001 inhibited the binding of Helicobacter pylori to human gastric-cell line MKN-45 cells by more than 90%. Spent culture supernatant of PL9001 rapidly decreased the viability of H. pylori, rupturing cell walls. The results suggest that PL9001 is a probiotic that can reduce the infectivity and persistence of H. pylori.
可存活和不可存活的迷惑魏斯氏菌菌株PL9001可使幽门螺杆菌与人类胃细胞系MKN-45细胞的结合减少90%以上。PL9001的培养上清液可迅速降低幽门螺杆菌的活力,使细胞壁破裂。结果表明,PL9001是一种可降低幽门螺杆菌感染性和持久性的益生菌。