van der Sluis I M, de Ridder M A J, Boot A M, Krenning E P, de Muinck Keizer-Schrama S M P F
Dept of Paediatrics, Subdivision of Endocrinology, Erasmus University Rotterdam, Rotterdam, Netherlands.
Arch Dis Child. 2002 Oct;87(4):341-7; discussion 341-7. doi: 10.1136/adc.87.4.341.
To obtain normative data on bone mineral density and body composition measured with dual energy x ray absorptiometry (DXA) from early childhood to young adulthood.
Cross sectional results from 444 healthy white volunteers (4-20 years) in the Netherlands were combined with the results from 198 children who agreed to participate in the follow up study approximately four years later. DXA (Lunar, DPXL) of lumbar spine and total body was performed to assess bone density and body composition.
Bone density and lean body mass (LBM) increased with age. Maximal increase in bone density and LBM occurred around the age of 13 years in girls and approximately two years later in boys. Bone density of total body and lumbar spine showed an ongoing slight increase in the third decade. Mean fat percentage in boys remained at 10.5% throughout childhood, but increased in girls.
Most of the skeletal mass in lumbar spine and total body is reached before the end of the second decade, with a slight increase thereafter. This study provides reference values for bone density and body composition measured with DXA for children and young adults.
获取从幼儿期到青年期采用双能X线吸收法(DXA)测量的骨密度和身体成分的标准数据。
将荷兰444名健康白人志愿者(4至20岁)的横断面结果与大约四年后同意参与随访研究的198名儿童的结果相结合。采用DXA(Lunar,DPXL)测量腰椎和全身的骨密度及身体成分。
骨密度和瘦体重(LBM)随年龄增长而增加。女孩骨密度和LBM的最大增幅出现在13岁左右,男孩约在两年后出现。全身和腰椎的骨密度在第三个十年仍有持续轻微增加。男孩的平均脂肪百分比在整个童年期保持在10.5%,但女孩有所增加。
腰椎和全身的大部分骨骼质量在第二个十年结束前达到,此后略有增加。本研究提供了儿童和青年采用DXA测量的骨密度和身体成分的参考值。