Di Bisceglie Adrian M
Division of Gastroenterology and Hepatology, Department of Internal Medicine, Saint Louis University School of Medicine, 3634 Vista Avenue, St. Louis, MO 63110, USA.
J Vasc Interv Radiol. 2002 Sep;13(9 Pt 2):S169-71. doi: 10.1016/s1051-0443(07)61783-7.
Hepatocellular carcinoma (HCC) is one of the most common internal malignancies worldwide. Until recently, it has occurred relatively rarely in the West. Now, however, it appears to be rising in incidence in the United States and other developed western countries. The most frequent underlying factors causing HCC are chronic viral hepatitis and cirrhosis. Common clinical features include abdominal pain and worsening of hepatic synthetic function. More recently, however, patients with asymptomatic tumors are being diagnosed because of more frequent screening and improvements in imaging techniques. Early detection of HCC is a key factor in improving outcomes of therapies. There is growing evidence that HCC may be prevented with strategies aimed at preventing or treating viral hepatitis.
肝细胞癌（HCC）是全球最常见的内部恶性肿瘤之一。直到最近，它在西方相对罕见。然而，现在美国和其他西方发达国家的发病率似乎在上升。导致HCC的最常见潜在因素是慢性病毒性肝炎和肝硬化。常见的临床特征包括腹痛和肝脏合成功能恶化。然而，最近，由于筛查更加频繁和成像技术的改进，无症状肿瘤患者也被诊断出来。早期发现HCC是改善治疗效果的关键因素。越来越多的证据表明，通过旨在预防或治疗病毒性肝炎的策略可以预防HCC。
