Kominski Gerald F, Simon Paul A, Ho Alex, Luck Jeffrey, Lim Yee-Wei, Fielding Jonathan E
Department of Health Services, University of California, Los Angeles (UCLA), School of Public Health, USA.
Public Health Rep. 2002 Mar-Apr;117(2):185-91. doi: 10.1093/phr/117.2.185.
This study was designed to assess the burden of disease and injury in the Los Angeles County population using Disability-Adjusted Life Years (DALYs), a composite measure of premature mortality and disability that equates to years of healthy life lost.
DALYs, stratified by gender and race/ethnicity, were calculated for 105 health conditions and aggregated groups of conditions for the Los Angeles County population for 1997. Years of Life Lost (YLLs) were calculated using 1997 county mortality statistics and published life tables. Years Lived with Disability (YLDs) were derived from age- and gender-specific disease incidence and disability data from the Global Burden of Disease Study.
DALYs produced a substantially different ranking of disease and injury burden than did mortality rates alone. The leading five causes of DALYs for males in the county were ischemic heart disease, violence, alcohol dependence, drug overdose and other intoxications, and depression. For females, the leading five causes were ischemic heart disease, alcohol dependence, diabetes, depression, and osteoarthritis. Differences in the rank order were also observed by race/ethnicity. The age-adjusted rate of DALYs for all health conditions combined was highest in African Americans (190 per 1,000), followed by American Indians (149 per 1,000), whites (113 per 1,000), Latinos (94 per 1,000), and Asians/Pacific Islanders (77 per 1,000).
The DALYs measure is a promising new tool to improve the capacity of local health departments and other health agencies to assess population health and establish an evidence base for public health decisions.
本研究旨在使用伤残调整生命年(DALYs)评估洛杉矶县人口的疾病和伤害负担,DALYs是一种将过早死亡和残疾综合起来的衡量指标,等同于失去的健康生命年数。
按性别和种族/族裔分层计算1997年洛杉矶县人口105种健康状况及综合状况组的DALYs。使用1997年县死亡率统计数据和已发表的生命表计算生命损失年数(YLLs)。伤残生命年数(YLDs)来自全球疾病负担研究中按年龄和性别划分的疾病发病率和残疾数据。
与仅用死亡率相比,DALYs得出的疾病和伤害负担排名有很大不同。该县男性DALYs的前五大原因是缺血性心脏病、暴力、酒精依赖、药物过量及其他中毒,以及抑郁症。对于女性,前五大原因是缺血性心脏病、酒精依赖、糖尿病、抑郁症和骨关节炎。不同种族/族裔在排名顺序上也存在差异。所有健康状况综合调整后的DALYs率在非裔美国人中最高(每千人190例),其次是美洲印第安人(每千人149例)、白人(每千人113例)、拉丁裔(每千人94例)和亚裔/太平洋岛民(每千人77例)。
DALYs衡量指标是一种很有前景的新工具,可提高地方卫生部门和其他卫生机构评估人群健康状况以及为公共卫生决策建立证据基础的能力。