从女性生殖道中常见分离出的乳酸杆菌对淋病奈瑟菌的抑制作用。
Inhibition of Neisseria gonorrhoeae by Lactobacillus species that are commonly isolated from the female genital tract.
作者信息
St Amant Diane C, Valentin-Bon Iris E, Jerse Ann E
机构信息
Department of Microbiology and Immunology, F. Edward Hebert School of Medicine, Uniformed Services University, Bethesda, Maryland 20814-4799, USA.
出版信息
Infect Immun. 2002 Dec;70(12):7169-71. doi: 10.1128/IAI.70.12.7169-7171.2002.
Abstract
Epidemiological studies suggest H(2)O(2)-producing lactobacilli protect women against gonorrhea. Here we demonstrate that Lactobacillus crispatus and Lactobacillus jensenii, the most common lactobacilli in the female genital tract, inhibit gonococci in both acidic and neutral pH conditions. Inhibition was neutralized by bovine catalase, suggesting that H(2)O(2) is the primary mediator of inhibition.
摘要
流行病学研究表明，产过氧化氢的乳酸杆菌可保护女性免受淋病感染。在此我们证明，卷曲乳酸杆菌和詹氏乳酸杆菌是女性生殖道中最常见的乳酸杆菌，它们在酸性和中性pH条件下均能抑制淋球菌。牛过氧化氢酶可中和这种抑制作用，这表明过氧化氢是抑制作用的主要介质。
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