山辣椒（Tabernaemontana pandacaqui Poir.）的抗炎、解热和镇痛活性
Anti-inflammatory, antipyretic and antinociceptive activities of Tabernaemontana pandacaqui Poir.
作者信息
Taesotikul T, Panthong A, Kanjanapothi D, Verpoorte R, Scheffer J J C
机构信息
Department of Pharmacology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.
出版信息
J Ethnopharmacol. 2003 Jan;84(1):31-5. doi: 10.1016/s0378-8741(02)00264-7.
Studies on carrageenin-induced rat paw edema, yeast-induced hyperthermia in rat and writhing response induced by acetic acid in mice showed that the alcoholic extract of stems of Tabernaemontana pandacaqui (T. pandacaqui) has significant anti-inflammatory, antipyretic and antinociceptive activities. These activities are due to alkaloidal components since they were also observed when the crude alkaloidal (CA) fraction separated from alcoholic extract was tested in the same models.
对角叉菜胶诱导的大鼠足爪水肿、酵母诱导的大鼠体温过高以及醋酸诱导的小鼠扭体反应的研究表明，黄花夹竹桃茎的乙醇提取物具有显著的抗炎、解热和镇痛活性。这些活性归因于生物碱成分，因为当从乙醇提取物中分离出的粗生物碱（CA）部分在相同模型中进行测试时也观察到了这些活性。
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