Soechitram S D, Chan S M, Nelson E A S, Brouwer A, Sauer P J J
Department of Paediatrics, University Hospital, Groningen, The Netherlands.
Food Addit Contam. 2003 Jan;20(1):65-9. doi: 10.1080/0265203021000031528.
The adverse effects of dioxins and polychlorinated biphenyls (PCBs) on human health are of increasing concern. These lipophilic compounds are concentrated through the food chain and are present in human milk. This study compares PCB levels in human milk samples from Hong Kong and Dutch mothers. Ten breast milk samples from Hong Kong and 10 from the Netherlands were collected during home visits between 2 and 6 weeks postpartum. Total toxic equivalence (TEQ) of dioxin and PCBs were determined using the DR-CALUX(R) bioassay. The total dioxin and PCB levels in breast milk samples for Hong Kong ranged from 3.1 to 29.9 pg TEQ g(-1) lipid and for the Netherlands from 8.9 to 89.5 pg TEQ g(-1) lipid. Despite Hong Kong's high degree of industrialization, the levels of dioxin and PCBs were fourfold lower in the Hong Kong than in the Dutch samples. This may be due to a lower dietary intake of dioxins and PCBs in Hong Kong because of lower background levels of these contaminants or to different food habits.
二噁英和多氯联苯（PCBs）对人类健康的不良影响日益受到关注。这些亲脂性化合物通过食物链富集，并存在于母乳中。本研究比较了香港和荷兰母亲母乳样本中的多氯联苯水平。在产后2至6周的家访期间，收集了10份来自香港的母乳样本和10份来自荷兰的母乳样本。使用DR-CALUX®生物测定法测定二噁英和多氯联苯的总毒性当量（TEQ）。香港母乳样本中二噁英和多氯联苯的总含量范围为3.1至29.9 pg TEQ g(-1)脂质，荷兰样本的范围为8.9至89.5 pg TEQ g(-1)脂质。尽管香港工业化程度很高，但香港母乳样本中的二噁英和多氯联苯含量比荷兰样本低四倍。这可能是由于香港这些污染物的背景水平较低，导致二噁英和多氯联苯的膳食摄入量较低，或者是由于饮食习惯不同。
