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旅行者腹泻的新出现病因:隐孢子虫、环孢子虫、等孢子球虫和微孢子虫。

Emerging Causes of Traveler's Diarrhea: Cryptosporidium, Cyclospora, Isospora, and Microsporidia.

作者信息

Goodgame Richard

机构信息

Baylor College of Medicine, Room BCMD 525D, Houston, TX 77030, USA.

出版信息

Curr Infect Dis Rep. 2003 Feb;5(1):66-73. doi: 10.1007/s11908-003-0067-x.

DOI:10.1007/s11908-003-0067-x
PMID:12525293
Abstract

Travel is a risk factor for acquiring infection with a spore-forming protozoa: Cryptosopridium, Cyclospora, Microsporidia, and Isospora. Certain travel destinations have a high disease burden and intense exposure. Patients present with persistent diarrhea and a history of recent travel to a developing country in the tropics. Very mild infections may be underdiagnosed and may cause typical traveler's diarrhea. In a patient with a history of travel and persistent diarrhea unresponsive to the usual antibiotic and antidiarrhea treatment, stool studies for all four of these protozoa infections should be performed. If immune status is normal and the disease is mild, symptomatic therapy may suffice. Effective treatment is available for Cyclospora, Microsporidia, and Isospora.

摘要

旅行是感染形成孢子的原生动物的一个风险因素,这些原生动物包括隐孢子虫、环孢子虫、微孢子虫和等孢子球虫。某些旅行目的地疾病负担高且暴露风险大。患者表现为持续性腹泻且近期有前往热带地区发展中国家的旅行史。非常轻微的感染可能诊断不足,并可能导致典型的旅行者腹泻。对于有旅行史且持续性腹泻对常规抗生素和止泻治疗无反应的患者,应进行针对所有这四种原生动物感染的粪便检查。如果免疫状态正常且病情较轻,对症治疗可能就足够了。对于环孢子虫、微孢子虫和等孢子球虫有有效的治疗方法。

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