Ameille J, Pauli G, Calastreng-Crinquand A, Vervloët D, Iwatsubo Y, Popin E, Bayeux-Dunglas M C, Kopferschmitt-Kubler M C
Institut Interuniversitaire de Médecine du Travail de Paris Ile-de-France, 45 Rue des Saints-Péres, 75270 Paris Cedex 06, France.
Occup Environ Med. 2003 Feb;60(2):136-41. doi: 10.1136/oem.60.2.136.
To estimate the general and specific incidence of occupational asthma in France in 1996-99; and to describe the distribution of cases by age, sex, suspected causal agents, and occupation.
New cases of occupational asthma were collected by a national surveillance programme, based on voluntary reporting, named Observatoire National des Asthmes Professionnels (ONAP), involving a network of occupational and chest physicians. For each case, the reporting form included information on age, sex, location of workplace, occupation, suspected causal agent, and methods of diagnosis. Estimates of the working population, used to calculate incidence rates by age, sex, region, and occupation, were obtained from the Institut National de la Statistique et des Etudes Economiques (INSEE) and from the French Securite Sociale statistics.
In 1996-99, 2178 cases of occupational asthma were reported to the ONAP, giving a mean annual rate of 24/million. Rates in men were higher than rates in women (27/million versus 19/million). The highest rate was observed in the 15-29 years age group (30/million). The most frequently incriminated agents were flour (20.3%), isocyanates (14.1%), latex (7.2%), aldehyde (5.9%), persulphate salts (5.8%), and wood dusts (3.7%). The highest risks of occupational asthma were found in bakers and pastry makers (683/million), car painters (326/million), hairdressers (308/million), and wood workers (218/million).
Despite likely underreporting, the number of cases of occupational asthma reported to the ONAP was approximately twice the number of compensated cases over the same period. The relevance of the programme is confirmed by the reproducibility of the results year after year, and its consistency with other surveillance programmes. The ONAP programme is useful for the identification of targets for primary prevention.
估算1996 - 1999年法国职业性哮喘的总体发病率和特定发病率;并按年龄、性别、可疑致病因素和职业描述病例分布情况。
职业性哮喘新病例由一项基于自愿报告的全国监测计划收集,该计划名为全国职业性哮喘观察站(ONAP),涉及职业医师和胸科医师网络。对于每例病例,报告表包含年龄、性别、工作场所位置、职业、可疑致病因素和诊断方法等信息。用于按年龄、性别、地区和职业计算发病率的劳动人口估计数来自法国国家统计与经济研究所(INSEE)和法国社会保障统计数据。
1996 - 1999年,有2178例职业性哮喘病例报告给ONAP,年平均发病率为24/百万。男性发病率高于女性(27/百万对19/百万)。15 - 29岁年龄组发病率最高(30/百万)。最常涉及的致病因素为面粉(20.3%)、异氰酸酯(14.1%)、乳胶(7.2%)、醛(5.9%)、过硫酸盐(5.8%)和木尘(3.7%)。职业性哮喘风险最高的是面包师和糕点师(683/百万)、汽车喷漆工(326/百万)、美发师(308/百万)和木工(218/百万)。
尽管可能存在报告不足的情况,但报告给ONAP的职业性哮喘病例数约为同期获得赔偿病例数的两倍。该计划结果年复一年的可重复性及其与其他监测计划的一致性证实了该计划的相关性。ONAP计划有助于确定一级预防目标。