Du Xiao-Ming, Sun Ning-Yi, Hayashi Jun, Chen Yang, Sugiura Minoru, Shoyama Yukihiro
Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka 812-8582 , Japan.
Phytother Res. 2003 Jan;17(1):30-3. doi: 10.1002/ptr.1057.
The pharmacological effects of an aqueous extract of the whole plants of in vitro cultured Anoectochilus formosanus were investigated experimentally for hepatoprotective and antihyperliposis activities. The extract showed significant antihepatotoxic activity against carbon tetrachloride induced cytotoxicity in primary cultured rat hepatocytes. In an assay for antihyperliposis using aurothioglucose-induced obese mice, the extract suppressed significantly the increase in the weights of body and liver, ameliorated triglyceride levels in the liver and serum, and also significantly reduced the deposition of adipose tissue.
对体外培养的台湾金线莲全草水提取物的药理作用进行了实验研究，以探讨其保肝和抗高血脂活性。该提取物对四氯化碳诱导的原代培养大鼠肝细胞毒性具有显著的抗肝毒性活性。在使用金硫葡萄糖诱导的肥胖小鼠进行的抗高血脂试验中，该提取物显著抑制了体重和肝脏重量的增加，改善了肝脏和血清中的甘油三酯水平，并且还显著减少了脂肪组织的沉积。
