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壶腹癌:38例病例回顾,重点关注治疗及预后因素

Carcinoma of the ampulla of Vater: Review of 38 cases with emphasis on treatment and prognostic factors.

作者信息

Makipour H, Cooperman A, Danzi J T, Farmer R G

出版信息

Ann Surg. 1976 Apr;183(4):341-4. doi: 10.1097/00000658-197604000-00002.

Abstract

Thirty-eight cases of carcinoma of the ampulla of Vater are presented. The diagnosis has been confirmed at laparatomy in all patients. Three operations were done, a pancreaticoduodenal resection in 23 patients, a biliary-enteric bypass in 7 patients and a biliary-enteric bypass plus excision of tumor in 8 patients. The operative mortality was 8% following resection, 14% following bypass plus excision of the ampulla and 13% following biliary-enteric bypass. Five patients survived 5 or more years. The longest survivors have followed pancreaticoduodenal resections (131 and 216 months). The level of bilirubin or presence of pain did not correlate with prognosis. Prognosis was better in the absence of nodal metastases, and in the presence of papillary tumors.

摘要

本文报告了38例 Vater壶腹癌病例。所有患者均经剖腹手术确诊。共进行了3种手术,23例行胰十二指肠切除术,7例行胆肠吻合术,8例行胆肠吻合术加肿瘤切除术。胰十二指肠切除术后手术死亡率为8%,壶腹切除加胆肠吻合术后为14%,单纯胆肠吻合术后为13%。5例患者存活5年或更长时间。存活时间最长的患者接受了胰十二指肠切除术(分别为131个月和216个月)。胆红素水平或疼痛的存在与预后无关。无淋巴结转移及存在乳头状肿瘤时预后较好。

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引用本文的文献

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Adenocarcinoma of the ampulla of Vater. A 28-year experience.壶腹腺癌。28年的经验。
Ann Surg. 1997 May;225(5):590-9; discussion 599-600. doi: 10.1097/00000658-199705000-00015.
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Adenocarcinoma of the ampulla of Vater. Diagnosis and treatment.壶腹腺癌。诊断与治疗。
Ann Surg. 1982 Feb;195(2):152-7. doi: 10.1097/00000658-198202000-00005.
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