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利用微卫星标记进行基因分型以区分来自种火鸡及其环境的烟曲霉分离株。

Differentiation between isolates of Aspergillus fumigatus from breeding turkeys and their environment by genotyping with microsatellite markers.

作者信息

Lair-Fulleringer Sybille, Guillot Jacques, Desterke Christophe, Seguin Dominique, Warin Stephan, Bezille Arnaud, Chermette René, Bretagne Stéphane

机构信息

UMR INRA-AFSSA-ENVA-UPVM Biologie Moléculaire et Immunologie Parasitaires et Fongiques, Ecole Nationale Vétérinaire d'Alfort, Maisons-Alfort, France.

出版信息

J Clin Microbiol. 2003 Apr;41(4):1798-800. doi: 10.1128/JCM.41.4.1798-1800.2003.

Abstract

To elucidate the epidemiology of the different forms of avian aspergillosis, 114 Aspergillus fumigatus isolates from sacrificed turkeys and 134 A. fumigatus isolates from air samples were collected and genotyped by microsatellite polymorphism marker analysis. Air sampling confirmed the huge diversity of A. fumigatus populations. Whereas older animals harbored several combinations of genotypes, 1-day-old chicks carried a unique genotype, suggesting a unique source of contamination.

摘要

为阐明不同形式禽曲霉菌病的流行病学,收集了114株来自屠宰火鸡的烟曲霉菌株和134株来自空气样本的烟曲霉菌株,并通过微卫星多态性标记分析进行基因分型。空气采样证实了烟曲霉菌种群的巨大多样性。老龄动物携带多种基因型组合,而1日龄雏鸡携带单一基因型,这表明存在单一污染源。

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本文引用的文献

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Microsatellite markers for typing Aspergillus fumigatus isolates.
J Clin Microbiol. 1998 Sep;36(9):2413-8. doi: 10.1128/JCM.36.9.2413-2418.1998.

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