Jones G S
Fertil Steril. 1976 Apr;27(4):351-6. doi: 10.1016/s0015-0282(16)41769-3.
In summary, the luteal phase defect is a deficiency of corpus luteum progesterone steroidogenesis, either in amount or duration, or both. The clinical manifestations include either primary infertility or repeated first trimester abortions. The diagnosis can only be made clinically on the basis of a well-timed endometrial biopsy that is read histologically as 2 or more days out of phase with the next period in at least two cycles.
总之,黄体期缺陷是指黄体孕激素生成不足,在量或持续时间方面,或两者皆有。临床表现为原发性不孕或反复早期流产。诊断只能在临床上通过适时的子宫内膜活检做出,经组织学检查,在至少两个周期中,子宫内膜与下一个月经周期不同步达2天或更长时间。